What is code, and can it be thought of like a magic spell? Are we building a world so complex that we will lose the ability to understand its operations -- and has that already happened? What does any of this have to do with SimCity, or knowledge that already exists but no one has put together, or how coding will evolve in the near future? Join Eagleman with scientist Sam Arbesman, who has just written a book asking the question: what is code, really?
Transcribed - Published: 14 July 2025
What is intelligence? If we look hard, can we find it in unexpected places: not just in brains but in all kinds of structures? How should we recognize it? And what does any of this have to do with a bipedal dog born without front legs, or making small new organisms out of single cells, or  how Wikipedia might be like an axolotl, or why we are so blind to the vast variety of minds that might surround us? Join Eagleman with guest Michael Levin, professor at Tufts, about how we might discover intelligence all around us in ways we don't typically intuit.
Transcribed - Published: 7 July 2025
Can we explain consciousness as emerging from classical neuroscience, or do we require deeper principles? Could quantum physics have something to do with it? Is it possible that consciousness predates biology, and biology evolved to take advantage of it? What are the right ways to build new theories in neuroscience when we don’t know the answers? Join Eagleman with Nobel laureate Roger Penrose and anesthesiologist Stuart Hameroff to explore the controversial idea that there could be, even possibly, any connection between quantum theory and our awareness of the world.
Transcribed - Published: 30 June 2025
Brains bear thoughts like a peach tree bears peaches. Even for meditators it's almost impossible to stop the firehose of words and images and ideas. But what in the world is a thought, physically? How can you hear a voice in your head when there's no one speaking in the outside world? And what does any of this have to do with a small marine animal who eats its own brain? Join Eagleman for this week's deep dive into our inner life.
Transcribed - Published: 23 June 2025
Is your brain a one-person show or an ensemble cast of rivaling neural networks? How do we manage the conflict between different drives, and what does this have to do with literature, deities, maturation, and what Nietzsche meant when he said “every drive wants to be master, and it attempts to philosophize in that spirit”? Join Eagleman this week with Jordan Peterson as we examine the way lives are built on conflicting wants.
Transcribed - Published: 16 June 2025
Is it possible to become happier? How much of your happiness has to do with genetics, social connection, comparison to other people, your balance of optimism vs pessimism, and whether it would be useful to keep a journal of your life? Join Eagleman this week with Bruce Hood, experimental psychologist and author of “The Science of Happiness”.Â
Transcribed - Published: 9 June 2025
How do brains slip so easily from the real world into made up worlds? What do authors of great literature have in common with stage magicians and comedians? What does any of this have to do with cognitive shortcuts, prediction machines, Marcel Proust, Toni Morrison, Jane Austen, or why jokes are always structured in threes? Join Eagleman this week for a conversation with his Stanford colleague Joshua Landy as they discuss brains on story.
Transcribed - Published: 2 June 2025
Why do movies work so well? What does film reveal about the way the brain processes reality? What does any of this have to do with omniscience, simulation, jumping around in time, or why dogs don’t do story? Join Eagleman with guest Jeffrey Zacks, cognitive scientist at Wash U, as we dive into the peculiar magic that happens when the lights go down, the screen glows to life, and we find ourselves pulled into the world of a film.
Transcribed - Published: 26 May 2025
Is AI an intelligent agent, or is there a different way we should be thinking about it? Is it more like a piece of cultural technology? What in the world is a piece of cultural technology -- and how would re-thinking this change our next steps? What does any of this have to do with the myth of the Golem, printing presses, Socrates, Martin Luther, or the story of stone soup? Join Eagleman this week with cognitive scientist Alison Gopnik for a new take on a new tech.
Transcribed - Published: 19 May 2025
If you had to give a detailed description of what flits through your mind, how good would you be at it? Might you be surprised at how many of your thoughts don't involve language? Are your thoughts changed by paying attention to them? What does this have to do with getting surprised by a random beep and immediately writing down what you’re thinking? Join Eagleman this week in conversation with Russell Hurlburt, a clinical psychologist who developed a new method to probe inner life.
Transcribed - Published: 12 May 2025
What would it take to get inside someone else's head, and could new brain technologies ever help us get there? Will there be dream celebrities, in which uploads go viral? What does consciousness feel like from the inside, and why do movies always get this wrong? Why don't you see your own blinks? What would it be like if exactly 1/2 of your brain was numbed to sleep? And what would it be like to become a horse?
Transcribed - Published: 5 May 2025
What does it mean to stand in another’s shoes—and when are the gaps between us too wide to cross? This week, Eagleman explores bats, kicked robots, Helen Keller, empathy, storytelling, and the phrase “I know exactly how you feel.” We'll weave through neuroscience, philosophy, literature, and technology to ask: Can we ever truly understand another’s inner world?
Transcribed - Published: 28 April 2025
What enables some people to keep going when everything falls apart? We all know someone who’s been through hell and comes out standing. This episode is about resilience. Join Eagleman with guest Dr. Jonathan Downar to discover what happens in the brain when we face adversity. Is resilience something you’re born with, or is it something your brain can develop? What does any of this have to do with The Diving Bell and the Butterfly, using magnetic fields to zap the brain, the less famous partner to the reward system, or what seemingly unrelated disorders in psychiatry all have in common?Â
Transcribed - Published: 21 April 2025
What does The Matrix tell us about the brain and time perception? And what does that have to do with champion bicyclists, hidden data, elementary particles, secret murderers, or time machines? Today’s episode is about slow motion: what’s going on in the brain, and why we are so mesmerized by it. Whether watching a sword battle, basketball dunk, or sprinters, we're pulled to slow motion like moths to flame... but have you ever wondered from a neuroscience perspective what that’s all about? Me too, and hence today’s 100th weekiversary episode.
Transcribed - Published: 14 April 2025
Your brain occasionally cooks up falsehoods that you believe entirely, but why does this confabulation happen, and how frequently? What does this tell us about memory, truth-telling, and your life as a story that drifts? And what does this have to do with a paralyzed Supreme Court judge, a blind person who insists she can see, whether Nelson Mandela did or did not die in the 1980s, or whether Curious George had a tail?
Transcribed - Published: 7 April 2025
How many people are having relationships with artificial neural networks? Should we think of AI lovers as traps, mirrors, or sandboxes? Is there a clear line between relationship bots and therapist bots? And what does this have to do with Eliza Doolittle, a doll cabinet in your head, loneliness epidemics, or suicide mitigation? Join Eagleman with guest researcher Bethanie Maples to discover where we are and where we're going.
Transcribed - Published: 31 March 2025
You're defined in part by the genome you arrive with -- so what does it mean when you can edit it? What does this have to do with viruses, copy-pasting, and whether we will modify the story of our own species? Join Eagleman with guest Trevor Martin, CEO of Mammoth Biosciences, for this week's episode about the remarkable situation we find ourselves in, now that we know how to read and write our biological inheritance.Â
Transcribed - Published: 24 March 2025
Now that we’re careening into our AI future, what are the most important things for our students to learn? Do we keep teaching as we always have, do we drop our heads on the desk, or are there clever ways to steer and optimize education? What would Sal Khan, founder of Khan Academy, say about all this? Find out in this week's episode.
Transcribed - Published: 17 March 2025
How can we rethink schools to meet the future? What does this have to do with the invention of the printing press, the prevalence of desk calculators, or the spread of Google? And how is this connected to the writer Goethe, a digital replica of the philosopher Aristotle, or the two lasting bequests that we should give our children? Join Eagleman this week for surprises about what AI means for the next generation.
Transcribed - Published: 10 March 2025
Do you perceive red the same way I do? What is wrong with the textbook model of vision? Why do brains have so many internal feedback loops? And what does any of this have to do with Plato’s cave, Ernest Hemingway, or artificial neural networks that perceive dogs everywhere? Join Eagleman with guest Anil Seth, author of “Being You”, to explore the scientific problem of consciousness.
Transcribed - Published: 3 March 2025
Meet David Eagleman - neuroscientist, author, and more. He is best known for his work on sensory substitution, time perception, brain plasticity, synesthesia, and neurolaw and is currently a neuroscientist at Stanford University. I thoroughly enjoyed picking his brain and I hope you enJOY too!
Transcribed - Published: 28 February 2025
How will creative people make a living in a world with AI? Is there a different way to think about the economy of the future -- and how might it involve mystifying and elevating humans? What does the term “data dignity" mean? Join Eagleman with guest Jaron Lanier -- computer scientist, artist, futurist -- as they discuss AI's boundless creative output and how we might thoughtfully navigate into the future.
Transcribed - Published: 24 February 2025
How are secrets in the brain like Abraham Lincoln’s political cabinet? Will AI in the near future hide things from you? And what does any of this have to do with political hierarchies, the formula for Coca-Cola, or deceptive chimpanzees? Join Eagleman to understand what neuroscience tells us about secrets: what they are, why they weigh on us, and how they sometimes grow into tangled webs we never meant to weave.
Transcribed - Published: 17 February 2025
What are we talking about neurobiologically when we talk about love? What does it have to do with how you were raised, the symmetry of someone's face, or the smell of their underarms? What do we learn from heartbreak, rom-coms, and little rodents called prairie voles? And what is the future of love & AI? Join Eagleman for a Valentine's Day special to learn what unseen sparks in the skull set the heart ablaze.
Transcribed - Published: 10 February 2025
A brain's 86 billion neurons are always chattering along with tiny electrical and chemical signals. But how can we get inside the brain to study the fine details? Can we eavesdrop on cells using other cells? What is the future of communication between brains? Join Eagleman with special guest Max Hodak, founder of Science Corp, a company pioneering stunning new methods in brain computer interfaces.
Transcribed - Published: 3 February 2025
Why do you like the taste of things that your friend doesn't? Why do kids not like coffee but adults do? What does any of this have to do with smelling people’s armpits, whether women really synchronize their menstruation, whether your culture eats a lot of spicy foods, and how animals sense the world? Join Eagleman this week to understand why there's no accounting for taste.
Transcribed - Published: 27 January 2025
Why is it so difficult to define intelligence? What does this have to do with being a fish in water trying to describe water? Might we humans possess one kind of intelligence in a constellation of many other types? And what does this have to do with empathy, AI, and our search for extraterrestrial life? Join Eagleman with guest Kevin Kelly as they dive into whether there might exist very different kinds of minds.
Transcribed - Published: 20 January 2025
Because visual signals take time to process, we live slightly in the past. So how do we ever catch a baseball? And what does this have to do with certain visual illusions, or the view in New York City, or the things you were never taught in school, or the warp drive in Star Trek? Join Eagleman this week for a mind blowing look at the strange relationship between vision and time.
Transcribed - Published: 13 January 2025
Are emotions something that happen to you, or are they bodily signals we interpret? Does everyone show emotions in the same way -- that is, are there particular markers of the face or the body that always mean anger, sadness, or joy? And what does this have to do with Charles Darwin, the truth about facial expressions, or the movie Inside Out? Join Eagleman with this week's guest, neuroscientist Lisa Feldman Barrett, author of hundreds of papers and "How Emotions are Made", for a deep dive into the truth about our feelings.Â
Transcribed - Published: 6 January 2025
Why are our brains so wired for love? Could you fall head over heels for a bot? Might your romantic partner be more satisfied with a 5% better version of you? How does an AI bot plug right into your deep neural circuitry, and what are the pros and cons? And what will it mean when humans you love don’t have to die, but can live on in your phone forever? Join Eagleman for a deep dive into relationships, their AI future, and what it all means for our species.
Transcribed - Published: 30 December 2024
What do charlatans have to understand about human perception? Why are you so bad at recognizing a real penny among fakes? What did Eagleman have to do with the redesign of the Euro, and why did he campaign to the European Central Bank that all their bills should be blank with a single hologram in the middle? In this episode, explore the crossroads of perception and deception. Brief appearance from special guest Adam Savage.Â
Transcribed - Published: 23 December 2024
Brains bear thoughts like a peach tree bears peaches. Even for meditators it's almost impossible to stop the firehose of words and images and ideas. But what in the world is a thought, physically? How can you hear a voice in your head when there's no one speaking in the outside world? And what does any of this have to do with a small marine animal who eats its own brain? Join Eagleman for this week's deep dive into our inner life.
Transcribed - Published: 16 December 2024
How can we understand music's effect on human brains? Is music universal or does it rely on your experiences? How is music similar to a language? Can music be leveraged to help anxiety, dementia, or Parkinson's disease? What does any of this have to do with Stevie Wonder on the high hat, or the relationship between music and color? Join Eagleman with guest Daniel Levitin -- neuroscientist, musician, and author of This Is Your Brain on Music and I Heard There Was A Secret Chord.
Transcribed - Published: 9 December 2024
Does our sense of self emerge from our brain's skill at lumping things into unchanging categories? What can we learn watching a caterpillar brain transition to a butterfly brain? Can we think of a memory as a pattern that stays alive and has its own life? Does an ant colony have a sense of self? Join Eagleman and biologist Michael Levin at Tufts – one of the most energetic and original thinkers in the field -- to dive into new territories of the self.
Transcribed - Published: 2 December 2024
Every cell in your body changes, so why do you have a sense of continuity of the self – as though you're the same person you were a month ago? What does this have to do with the watercraft of the Greek demigod Theseus, or the End-of-History illusion, or why you go through so much trouble to make things comfortable for your future self, even though you don't know that person? And if there really were an afterlife, what age would your deity make everyone for living out their eternities? Join this week for a two-parter about the mysteries of selfhood.
Transcribed - Published: 25 November 2024
Two certainties are death and taxes; a third is that people will work hard to avoid them both. But why is it so difficult to extend our lifespan? We know how to do it in worms and mice; why is it tricky in humans? Why do so few companies study longevity? What does the near future hold? What would it be like if everyone lived a much longer life? Join Eagleman this week with longevity expert Martin Borch Jensen to discuss the hopes and challenges of longevity science.
Transcribed - Published: 18 November 2024
Why do brains dream, and why are dreams so bizarre? Why doesn't your clock work in your dreams? And even though you spend much of your working day looking at your cell phone and computer – why do they almost never make appearances in your dream content? Is dream content the same across cultures and across time? Are dreams experienced in black & white, or in color? Are dreams the strange love child of brain plasticity and the rotation of the planet? What is the relationship between schizophrenia and dreaming? In the future, will we be able to read out the content of somebody's dream? Join Eagleman this week to learn why and how we spend a fraction of our sleep time locked in different realities, swimming in plots which aren't real but which compel us entirely nonetheless.
Transcribed - Published: 11 November 2024
What is depression? Why are brains able to slip into it? Is depression detectable in animals? Do animals have options beyond fight or flight? And what does any of this have to do with measuring depression medications in city water supplies, reward pathways in the brain, the prevalence of tuberculosis, and zapping the head with magnetic stimulation? Join today's episode with David Eagleman and his guest -- psychiatrist Jonathan Downar -- for a deep dive into the brain science behind depression and what new solutions are on the horizon.
Transcribed - Published: 4 November 2024
Why can you hear some sounds two different ways, depending on which word you’re looking at? Why do electrical outlets sometimes look like a face? How can you have rich visual experience with your eyes closed? Are some crosswalk buttons fake? Why are some pictures interpretable only once you’ve been told what to look for? And although brains are often celebrated for their parallel processing, what should they really be celebrated for? Tune in to learn what happens when the raw facts of the world collide with your expectations.
Transcribed - Published: 28 October 2024
When he was a child, Eagleman fell off a roof and time seemed to run in slow motion. When he became a neuroscientist, he grew curious about the experience and collected hundreds of similar stories from others. But is it true that your brain can actually see in slow motion, like Neo in the Matrix? And how would you test that? Hear how he dropped volunteers from a tower to put the science to the test, and what the answer reveals about our perception, memory, and experience of the world.
Transcribed - Published: 21 October 2024
What would it be like to have a vastly better memory than you do now? What if you could remember what you were wearing on any day a dozen years ago? Or who you were with, what the conversation was, and whether it rained? Would it be a blessing or a curse? And if you’re forgetting a lot of your life, what might you do to better remember it? Join Eagleman with actress Marilu Henner, one of only dozens of people in the world diagnosed with highly superior autobiographical memory.
Transcribed - Published: 14 October 2024
When you imagine something -- like the sun peeking over a mountain during an early morning rainstorm -- do you see it with rich visual detail, or instead with very little internal picture? In an earlier episode we tackled the spectrum of visual imagination, from hyperphantasia to aphantasia -- and in this episode we dive even deeper with guest Joel Pearson to surface the most surprising differences between people's internal lives. How does your experience differ from other people's, and how does your brain cobble together the skills you have to accomplish what you need?
Transcribed - Published: 7 October 2024
Why do you see a unified image when you open your eyes, even though each part of your visual cortex has access to only a small part of the world? What is special about the wrinkled outer layer of the brain, and what does that have to do with the way that you explore and come to understand the world? Are there new theories of how the brain operates? And in what ways is it doing something very different than current AI? Join Eagleman with guest Jeff Hawkins, theoretician and author of "A Thousand Brains" to dive into Hawkins' theory of many models running in the brain at once.
Transcribed - Published: 30 September 2024
How do you define what things are living and dead? You might look at a sprinting cheetah and say it's clearly alive, whereas a chunk of rock is not -- but where do we draw the line? What might we expect extraterrestrials to look like, and would we even have the capacity to recognize them? And what does any of this have to do with Frankenstein, ancient Greek philosophers, or the possibility of finding a cell phone on Mars? Join Eagleman with guest Sara Walker, theoretical physicist at Arizona State University and author of the book “Life as No One Knows It”.Â
Transcribed - Published: 23 September 2024
Do brains time travel? What is a prediction error? What does any of this have to do with the 2008 crash of the economy, how we keep internal price tags, or a rational approach to drug addiction in society? Join Eagleman to learn how your 3-pound universe spends its whole existence nailing down choices.
Transcribed - Published: 16 September 2024
When you make a decision about what food to order, what's happening in your brain? How do you clinch long-term decisions, like hitting the gym instead of doomscrolling? And what does any of this have to do with the ancient Greeks, alien hand syndrome, and constraining a president who wants to launch a nuclear bomb? Join Eagleman this week and next to discover how your brain weighs alternatives and nails down decisions.
Transcribed - Published: 9 September 2024
From the brain’s point of view, what is humor? When something is funny, why do we breathe in and out rapidly? Do other animals laugh? Why do most jokes come in threes? What do mystery novelists, magicians, and comedians have in common? Could AI be truly funny? Join Eagleman this week to appreciate the tens of reasons and millions of years behind the tickling of your neural pathways.
Transcribed - Published: 2 September 2024
What does neuroscience have to do with investment, and what does that have to do with Isaac Newton, the Dutch East India company, Kodak, the way zebras herd, our emotions, and almost 200 cognitive biases? Join Eagleman with guest Mark Matson, whose new book The American Dream dives into the cognitive illusions we face when trying to make investments.
Transcribed - Published: 26 August 2024
You know that moment in the horror movie where the monster is coming closer, but the movie star doesn't see it? Why does that drive you crazy, and what does that teach us about brains? What is theory of mind, and why is it so important for everyone from poker players to conmen to stage magicians to novelists? Join us this week to dive into a fundamental skill of human brains -- and the question of whether current AI has any ability to simulate other people's minds.
Transcribed - Published: 19 August 2024
Is your notion of yourself built on narrative that may or may not be accurate? If someone told you an entirely false story about yourself, could you come to believe it? What does that have to do with six people who spent over a decade in prison together for a crime they didn't commit? Join Eagleman for part 2 of some mind-blowing conclusions about your account of your own life.
Transcribed - Published: 12 August 2024
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