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CRYPTO 101

Ep. 660 Sei Labs State of the Union

CRYPTO 101

Bryce Paul & Brendan Viehman

Business, Investing

4.6821 Ratings

🗓️ 14 June 2025

⏱️ 23 minutes

🧾️ Download transcript

Summary

Justin Barlow, head of Business Development at the Sei Foundation, discussed the unique positioning of Sei as an EVM-compatible, high-throughput blockchain that addresses limitations seen in other networks like Ethereum. The Sei Foundation focuses on driving ecosystem growth through investments in diverse sectors like DeFi, gaming, social networks, and emerging areas like AI and decentralized science (DeSci), with a recent $65 million fund dedicated to DeSci projects. Sei operates as a fully independent blockchain with its own infrastructure, aiming to provide developers with opportunities to build complex on-chain applications that were previously too expensive or technically challenging. The upcoming Sei Giga upgrade promises to significantly increase transaction capacity to over 200,000 transactions per second, potentially enabling large-scale applications to run on blockchain infrastructure.


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Transcript

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0:00.0

All right. Well, I'm joined now by an incredible guest. Very honored to have Justin Barlow join us, who's the head of BD, business development and investments at the SAFE Foundation. Justin, thank you for joining us today at

0:21.8

the Crypto Hedge Fund Summit. How are you doing? Thank you so much for having me. Doing well.

0:26.4

Good, good, man. Well, hey, look, I'm excited about what's going on at Say. I'm staking some say.

0:32.8

So full disclosure, I have exposure. I always like to be forthcoming and transparent about that. But

0:38.6

I've been really excited about what you guys have been doing. We spoke with Jay, Jay Yog, who's one of

0:45.5

the co-founders over there at Say some time ago. And we were just very, very impressed. And so we

0:52.6

want to get into what's going on at the SAFE Foundation and how you're developing that and investing in the ecosystem.

0:59.0

But before we do, we just want to get acquainted with you personally.

1:02.4

You know, how did you get into this industry and what were you doing a little bit before?

1:06.3

Just high level.

1:07.9

Yeah.

1:08.5

I mean, I am lucky enough to say that I am probably part of this sort of first generation

1:14.4

of true crypto natives.

1:17.1

Had gotten to crypto when I was quite young, was really one of my first sort of forays into

1:23.1

the professional world.

1:24.6

So launched a fund originally back in 2017, so just about eight years ago now,

1:32.1

had gotten into crypto a little bit before that. And that fund was really dedicated towards,

1:36.7

you know, basically a full sort of long short strategy, right? So a typical hedge fund entirely

1:43.6

on the liquid side and ran that for a number of years.

1:48.1

What ended up happening was I sort of continued, you know, running that fund for, again, a few years,

1:54.3

spent some time in the sort of long-form research and content side of things, spent some time with some trad-fi institutions like Millennium Management in New York,

2:04.6

in the endowment by alma mater, University of Southern California.

...

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