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Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Ep. 603 The Microbiome's Role in Heart and Metabolic Health with Dr. William Davis | Menopause, Perimenopause, Microbiome

Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Cynthia Thurlow

Science, Life Sciences, Health & Fitness, Nutrition, Alternative Health

4.71.2K Ratings

🗓️ 6 June 2026

⏱️ 64 minutes

🧾️ Download transcript

Summary

Today, I am delighted to reconnect with Dr. William Davis. He’s a cardiologist, New York Times bestselling author of the Wheat Belly book series, and author of Super Gut. He is also the founder and Medical Director of the Infinite Health Program and the co-founder and Chief Medical Officer of Realize Therapeutics Corp, which is developing innovative solutions to restore and support the human microbiome. In our conversation, we explore the microbiome and how it is influenced by key changes in a woman’s life, including pregnancy and premature delivery, as well as how modern lifestyle factors disrupt our microbiome. Dr. Davis discusses endotoxemia and dysbiosis in fertility, uterine health, and cardiovascular disease, as well as antibiotic use, statins, atrial fibrillation, the role of blood glycocalyx, TMAO, and the dietary approach he considers important. He also discusses appropriate prescribed antibiotic use in the context of microbiome disruption. Stay tuned for another fascinating discussion with Dr William Davis on the far-reaching impact of the microbiome on women's health, heart health, and longevity. I look forward to having Dr. Davis back on the show! IN THIS EPISODE, YOU WILL LEARN: How factors such as omega-3 fatty acid intake and microbiome health may affect pregnancy outcomes. How microbial health extends beyond the gastrointestinal tract and can influence multiple organ systems The disruptive effects of antibiotics, glyphosate, food preservatives, and emulsifiers on the microbiome Dr. Davis describes how endotoxemia can affect the brain, skin, joints, metabolism, and cardiovascular system. How endotoxemia influences multiple cardiovascular risk markers How endotoxemia and glycation can contribute to atrial fibrillation The role of the glycocalyx, and how damage to the integrity of the glycocalyx could influence arterial function and cardiovascular risk Why fermented foods remain a key strategy for microbiome diversity Dr. Davis shares his dietary choices and his approach to microbiome support  Bio: William Davis, MD  William Davis, MD, is a cardiologist and #1 New York Times bestselling author of the Wheat Belly series of books, as well as Undoctored and Super Gut. Recent human clinical trials that Dr. Davis conducted have revealed that it is possible to lose fat weight while preserving muscle, thereby preventing weight regain and enjoying improved body composition, findings that inspired the writing of Bulge. Dr. Davis is also Chief Medical Officer at Realize Therapeutics Corp., which he co-founded to explore the new science of the microbiome to improve health and appearance, including body composition. Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website. Submit your questions to support@cynthiathurlow.com  Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.  Purchase Cynthia’s book, The Menopause Gut. Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Connect with Dr. William Davis On his website Join Dr Davis’s Inner Circle Dr. Davis’s books

Transcript

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0:00.0

Welcome to Everyday Wellness Podcast.

0:03.6

I'm your host, nurse practitioner, Cynthia Thurlow.

0:07.4

This podcast is designed to educate, empower, and inspire you to achieve your health and wellness goals.

0:13.8

My goal and intent is to provide you with the best content and conversations from leaders in the health and wellness industry each week and impact over a million lives.

0:29.1

Today, I had the honor of reconnecting with fan favor Dr. William Davis.

0:34.1

He's a cardiologist and New York Times best-selling author of the Wheat Belly

0:38.6

book series. He's also a medical director and founder of the Infinite Health Program and

0:43.1

chief medical officer and co-founder of Realized Therapeutics Corp that is developing innovative

0:48.5

solutions for the disrupted human microbiome and author of the book Super Gut. Today we spoke about how the microbiome is

0:57.6

influenced by key changes in a woman's life, including premature delivery, how our modern

1:04.0

lifestyle is disrupting our microbiome, the influence of specific endotoxins for fertility and uterine health, statistics on antibiotics

1:15.3

use, and how this influences not only the development of endotoxemia and dysbiosis, but also

1:22.6

increases our risk of developing cardiovascular disease. The impact of statins, the role of endotoxemia

1:30.3

in recurrent atrial fibrillation, cardiovascular disease, specific challenges navigating

1:36.4

our current health care paradigm, the role of the Gygokalix, TMAO, dietary scripts that he follows and thinks are particularly important and

1:46.8

how he addresses and makes suggestions around appropriately prescribed antibiotic use.

1:52.9

Always a fascinating conversation with Dr. Davis, easily one of my favorite recent conversations

1:58.8

I've had on the podcast, and why he will be likely back

2:02.5

for a third conversation, if not later this year, early in 2027.

2:10.0

Dr. Davis, so good to have you back on the podcast. Welcome back to Everyday Wellness.

2:14.1

Thanks for having me. Yeah. I know in our last conversation, which we covered so much

2:19.1

information surrounding the gut, and at the very end, the inflection point, you said, I'd love to

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