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Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Ep. 591 Inflammation Is Aging You Faster Than You Think! – The Shocking Truth About Blood Sugar, Muscle & Longevity with Dr. Paul Reynolds | Menopause, Perimenopause & Metabolic Health

Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Cynthia Thurlow

Science, Life Sciences, Health & Fitness, Nutrition, Alternative Health

4.71.2K Ratings

🗓️ 9 May 2026

⏱️ 63 minutes

🧾️ Download transcript

Summary

Today, I’m delighted to connect with Dr. Paul Reynolds, whom I was honored to meet at an event last year. He is a professor of cell biology and physiology at Brigham Young University. In our discussion, we explore inflammation, how it changes with aging, and how muscle serves as both an endocrine and a metabolic organ. We unpack glucose physiology, how it drives inflammation in the body, and examine the effects of glycation and the changes it causes in our eyes, immune systems, nerves, skin, and bones. Dr. Reynolds explains his “rules” for glucose balancing and the benefits of micro-dosing with GLP-1s, or starting with a minimal dose and increasing it slowly. We also discuss cravings and gender differences in men and women, and share practical strategies that everyone can use. I am looking forward to recording another podcast episode with Dr. Reynolds later this year, when his new book comes out. IN THIS EPISODE, YOU WILL LEARN: Chronic inflammation as the root of many modern health issues Muscle loss with aging and its link to inflammation and glycation How excess glucose fuels free radicals, glycation, and inflammation What glycation is and why it damages the body Lifestyle habits that disrupt glucose balance and drive inflammation Supporting natural GLP-1 through diet and lifestyle Fasting and smart carb intake for insulin sensitivity Menopause, autoimmunity, and chronic disease risk Long-term consequences of glycation for the eyes, skin, bones, immune system, and nerves Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow  Cynthia’s Menopause Gut Book is on presale now! Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause Supplement Line Connect with Dr. Paul Reynolds On X, Instagram, and YouTube

Transcript

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0:00.0

Welcome to Everyday Wellness Podcast.

0:04.0

I'm your host, Nurse Practitioner Cynthia Thurlow.

0:07.0

This podcast is designed to educate, empower, and inspire you to achieve your health and wellness goals.

0:13.0

My goal and intent is to provide you with the best content and conversations from leaders in the health and wellness industry each week and impact over a million lives.

0:29.1

Today I had the honor of connecting with Dr. Paul Renner, so I had the honor of meeting when I was at an event earlier this past year. He is a professor of cell biology

0:40.6

and physiology at Brigham Young University. Today we spoke about inflammation and how this

0:46.8

shifts and changes with the aging process, how muscle is both an endocrine and metabolic organ,

0:53.7

glucose physiology, and how it drives inflammation

0:57.1

in our body, the impact of glycation, his blood glucose balancing rules, why he thinks

1:04.2

GLP1s used in microdosed or small amounts with titration are very useful. What drives cravings? Key gender differences

1:14.0

between men and women. How glycation drives changes in our eyes, our immune system, our nerves,

1:22.7

our skin and bones. And last but not least, tangible takeaway strategies that everyone can use from this episode.

1:30.3

I look forward to having Dr. Reynolds back when his new book comes out later this year.

1:38.1

Dr. Reynolds, such a pleasure to have you on the podcast. Welcome to Everyday Wellness.

1:42.7

Thank you. Thanks, Cynthia. It's great to be here.

1:45.1

I would love to start the conversation today, kind of talking about how the perimenopause

1:50.9

and menopause transition changes insulin sensitivity and metabolic health and women. Because

1:56.2

metabolic flexibility becomes a larger conversation. Maybe this is something that individuals haven't really

2:02.1

thought about until they get to be middle age and they start wondering why they're struggling with

2:06.3

weight loss resistance or they're losing skeletal muscle mass. But talk to us about some of the changes

2:12.0

that are happening, not just for women, but also for men. Yeah, that's a great introduction, very

2:17.0

specific. And if I could just maybe

...

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