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Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Ep. 587 “Your Body is a Chemistry Lab!” – Why Counting Calories Fails in Midlife | Menopause & Hormones

Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Cynthia Thurlow

Science, Life Sciences, Health & Fitness, Nutrition, Alternative Health

4.71.2K Ratings

🗓️ 30 April 2026

⏱️ 28 minutes

🧾️ Download transcript

Summary

Welcome to another episode in our Midlife Minute Series. Today, I’ll be exploring weight loss resistance and how you may be unknowingly disrupting your hormones during perimenopause and menopause. Stay tuned for more! IN THIS EPISODE, YOU WILL LEARN: Why  the concept of calories in, calories out is outdated How sleep, stress, and sarcopenia drive weight loss resistance in midlife Why under-eating protein and over-consuming processed carbohydrates become more problematic in middle age Why increasing your protein intake without consuming enough fiber can cause gut issues Why constant snacking and poor food quality compound metabolic dysfunction How dysbiosis adds to weight loss resistance, poor metabolic health, and sleep disruption How everyday exposure to toxins contributes to inflammation, oxidative stress, and insulin resistance, and disrupts hormone signaling Why perimenopause becomes a “litmus test” for how well we take care of ourselves Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website. Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community: The Midlife Pause/Cynthia Thurlow.  Cynthia’s Menopause Gut Book is on presale now! Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause Supplement Line

Transcript

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0:00.0

Welcome to Everyday Wellness Podcast. I'm your host, nurse practitioner, Cynthia Thurlow.

0:07.3

This podcast is designed to educate, empower, and inspire you to achieve your health and wellness goals.

0:13.7

My goal and intent is to provide you with the best content and conversations from leaders in the health and wellness industry each week and impact over a million lives.

0:29.0

This is the start of a new Thursday series called The Midlife Minute that is really designed to address listeners questions in a little bit longer

0:40.3

length of time and or deeper dive into topics. Ideally, we're going to keep these podcasts under

0:47.3

20 minutes. Occasionally, we may go over to 30, but I'm trying to reinforce some key concepts and ensure that I'm addressing listeners' questions

0:58.5

in a way that's really helpful.

1:00.5

So the questions that I will be addressing topics are going to be items that I'm being asked

1:05.2

over and over and over again.

1:06.5

I hope you enjoy this series.

1:08.1

Please share with your friends.

1:09.7

And as you know, you can always send

1:11.7

your questions to support at cynthia thurlow.com. I appreciate each and every listener.

1:20.5

According to Dr. Sarah Gottfried Zahl, 99% of weight loss resistance is hormonal.

1:33.7

And so we've kind of been conditioned to believe that it's all about calories and calories out.

1:34.1

And I'm going to make the argument today why I think that is largely ineffective.

1:38.8

And as the esteemed JJ Virgin says, your body is a chemistry lab, not a bank account, and calories in,

1:46.9

calories out, or SICO is woefully outdated. So what actually is a calorie? It was coined in the

1:55.6

1800s and was used by scientists who measure energy in all of its different forms by the same metric as heat,

2:03.5

light, motion, or the potential energy of chemical bonds. And these chemical bonds are found in most

2:10.8

foods and can release their potential energy as heat and light when burned. And then in 1887, Wilbur atwater,

2:20.5

father of modern nutritional science,

...

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