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Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Ep. 580 Why Women’s Heart Disease Skyrockets After 40 – The Shocking Truth About Hormones, Toxins & Testing with Dr. Christopher Davis | Menopause & Heart Disease

Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Cynthia Thurlow

Science, Life Sciences, Health & Fitness, Nutrition, Alternative Health

4.71.2K Ratings

🗓️ 15 April 2026

⏱️ 63 minutes

🧾️ Download transcript

Summary

Today, I am honored to welcome Dr. Christopher Davis, a triple-board-certified physician in internal medicine, cardiology, and interventional cardiology, as well as a specialist in functional and regenerative medicine. He is also the Chief Cardiologist at Humann, a science-backed, plant-based heart health supplements company.  In our discussion, Dr Davis and I explore why women’s risk for heart disease accelerates after 40, how women’s physiology and anatomy make them more prone to small vessel disease, the challenges of our current medical model, and the impact of toxins. Dr. Davis shares the labs and imaging modalities he prefers, and highlights the need for personalized medicine. We examine cardiomyopathies in women, where takotsubo or broken heart syndrome originates, and how declining nitric oxide production during perimenopause and menopause affects vascular health. We also cover research on GLP-1s and their impact, the significance of nitric oxide production, the importance of endothelial health, and the glycocalyx. Today’s discussion is a must-listen for anyone seeking a deeper understanding of women’s heart health in middle age. IN THIS EPISODE, YOU WILL LEARN: Why women’s heart disease risk accelerates after 40 How toxins and xenoestrogens contribute to vascular stress and metabolic disruption What advanced labs and imaging can reveal beyond traditional testing Why women’s unique physiology makes them more vulnerable to small vessel disease How the glycocalyx and endothelial health protect the heart and circulation Why personalized medicine is essential Why cardiomyopathies like takotsubo are seen more frequently in women How nitric oxide production impacts vascular flexibility and overall cardiac health What research shows about the benefits of GLP-1s, beyond weight loss The value of the Goldilocks approach to supplements in personalized patient care Bio: Christopher Davis, MD, FACC Dr. Christopher Davis is triple board-certified in internal medicine, cardiology, and interventional cardiology and is a specialist in functional medicine, bioidentical hormone replacement, and regenerative medicine. He is the Chief Cardiologist at Humann, a science-backed, plant-based heart health supplements company. Dr.Davis has been honored as one of America’s “Top Doctors” by Castle Connolly Medical and has received the distinguished title of Top Doctor by U.S. News and World Report and Sarasota Magazine. Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community (The Midlife Pause/Cynthia Thurlow)  Cynthia’s Menopause Gut Book is on presale now! Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause supplement line Connect with Dr. Christopher Davis Reveal Vitality On Instagram

Transcript

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0:00.0

Welcome to Everyday Wellness Podcast.

0:03.7

I'm your host, nurse practitioner, Cynthia Thurlow.

0:07.4

This podcast is designed to educate, empower, and inspire you to achieve your health and wellness goals.

0:13.9

My goal and intent is to provide you with the best content and conversations from leaders in the health and wellness industry each week and impact

0:22.1

over a million lives.

0:28.8

Today, I had the honor of recording with Dr. Christopher Davis, who is a triple board certified

0:34.2

physician in internal medicine cardiology and interventional cardiology and also

0:39.2

a specialist in functional medicine and regenerative medicine. He's also the chief cardiologist

0:44.9

at human, a science-backed plant-based heart health supplements company. Today, Dr. Davis and I talked

0:51.3

about why women's heart disease risk accelerates after 40, challenges to our

0:57.4

current prevailing medical model, the impact of toxins including xenoestrogens, and specific

1:04.6

testing that he likes to utilize as well as infrared sauna, why labs and imaging matter,

1:13.4

and specifically which labs he likes to look at, and diagnostic modalities, including clearly, why women have unique physiology and anatomy

1:21.1

for small vessel disease, and the impact on the reduction of nitric oxide production in

1:26.9

perimenopause and menopause, the importance

1:29.2

of the glyco calyx and our endothelial health, why personalized medicine is so important, as well as

1:37.0

challenges of the traditional allopathic model, why we see more cardiomyopathies in women and

1:43.1

specifically what Takasobo or Broken Heart

1:46.3

Syndrome cardiomyopathy originates from, the impact of GLP-1s and recent research.

1:51.8

And last but not least, specific supplements that Dr. Davis likes to utilize with his patient

1:57.7

population, as well as the important of nitric oxide production and specific

2:03.1

Goldilock effects that he likes to consider when treating patients. This is an informative and

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