Today, I’m thrilled to reconnect with Dr. Rocio Salas-Whalen, a board-certified endocrinologist and obesity medicine specialist with more than 15 years of clinical experience, widely recognized as one of the earliest adopters of GLP-1 therapies in the United States. She is also the author of the upcoming book Weightless: A Comprehensive Guide to the New Era of GLP-1 Medications. In our discussion, we explore the transgenerational impact of obesity as a complex, chronic, and deeply multifactorial condition. We discuss the effects of environmental exposures and trauma, the essential role of education in overcoming weight-loss resistance and managing obesity, and the physiological changes women experience in the perimenopause-to-menopause transition. We explain the importance of body positivity and image, reframing our thoughts around obesity and being overweight, and why building and maintaining muscle is non-negotiable. We dive into the physiology of GLP-1 medications and specific targets for women in perimenopause and menopause, ways to address weight-loss stalls, and the effects of the weight bias so deeply entrenched in our society. Dr. Salas Whalen also shares her thoughts on alternatives and additions to GLP-1 therapies, clarifying the importance of protein and strength training while using GLP-1 drugs.  This conversation with Dr. Salas-Whalen is truly invaluable, and I highly recommend her upcoming book, Weightless. IN THIS EPISODE, YOU WILL LEARN: • What people come to understand about “normal eating” after starting GLP-1s • How GLP-1s interrupt the binge–guilt–shame cycle • The role GLP-1s play in helping people stay in control of food rather than letting food control them • Strategies for avoiding side effects when using GLP-1 medications • Why certain foods trigger problems on injection days • Importance of proper guidance to prevent severe side effects • The impact a prescriber’s guidance has on your success with GLP-1s • Why treatment plans must be tailored to each patient’s needs and metabolism • Factors doctors consider when deciding whether to add additional medications to a GLP-1 plan Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to support@cynthiathurlow.com Join other like-minded women in a supportive, nurturing community (The Midlife Pause/Cynthia Thurlow)  Cynthia’s Menopause Gut Book is on presale now! Cynthia’s Intermittent Fasting Transformation Book The Midlife Pause supplement line Connect with Dr. Rocio Salas-Whalen Website On social media: @drsalaswhalen Dr. Rocio’s Book, Weightless - Pre-order now! (Releases 12-30-25)