Ep. 523 This Is Why Your Cholesterol Shifts in Midlife – The Best Strategies to Reduce Risk & Improve Vascular Health with Dr. Thomas Dayspring

Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Cynthia Thurlow

Alternative Health, Nutrition, Science, Life Sciences, Health & Fitness

4.8 • 1K Ratings

🗓️ 26 November 2025

⏱️ 78 minutes

🔗️ Recording | iTunes | RSS

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Summary

I am excited to reconnect with Dr. Tom Dayspring today. He joined me before for an extremely popular seven-part podcast series where we tackled topics related to lipids and the physiological shifts that occur as we transition from perimenopause into menopause. Dr. Dayspring graciously agreed to return today for an Ask Me Anything episode, where we explore how lipids change as we navigate the perimenopause-to-menopause transition and discuss the significance of bioindividuality, inflammation, vascular health, and endothelial function in the context of changing estrogen levels. Dr. Dayspring also clarifies how visceral fat affects lipid levels, and we discuss testing for cardiovascular disease, the relevance of particle size, LPIR scores, and physical markers of insulin resistance. Stay tuned for today’s valuable and fascinating conversation. I will share the second AMA with Dr. Dayspring later this fall. IN THIS EPISODE, YOU WILL LEARN: How estrogen loss impacts lipid metabolism in midlife Shifts in vascular health that occur during the menopause transition What makes endothelial function central to long-term health? Why triglycerides matter more than you think How variations in LDL particle size influence cardiovascular risk What standard cholesterol tests could miss about your cardiovascular health How inflammation can alter your lipid profile How your genes and lifestyle shape your lipid profile Markers women need to track over and above standard cholesterol tests How menopause reshapes women’s cardiovascular risk profile Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to [email protected] Connect with Dr. Thomas Dayspring On X (@DrLipid) On LinkedIn

Transcript

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0:00.0	Welcome to Everyday Wellness Podcast.
0:03.7	I'm your host, nurse practitioner, Cynthia Thurlow.
0:07.4	This podcast is designed to educate, empower, and inspire you to achieve your health and wellness goals.
0:13.9	My goal and intent is to provide you with the best content and conversations from leaders in the health and wellness industry each week and
0:21.5	impact over a million lives.
0:29.0	Today I had the honor of reconnecting with Dr. Tom Dayspring, who has been part of an exceedingly
0:36.5	popular series of podcasts. There are seven prior podcasts,
0:41.5	discussing topics related to lipids and shifts in our physiology as we navigate perimenopause
0:51.3	into menopause. Today he returned graciously to do and ask me anything and we
0:57.0	started off discussing how lipids change navigating the perimenopause to menopause transition,
1:03.0	the impact of bio-individuality, the role of inflammation, vascular health, and endothelial
1:09.0	function in the setting of changes in estrogen,
1:13.0	how visceral fat impacts are lipids, testing for cardiovascular disease, the relevance of particle
1:20.4	size, L-P-I-R scores, and physical markers of insulin resistance. As always, again, another invaluable conversation with Dr. Dayspring.
1:32.3	Stay tuned for the second AMA that will be shared later this fall.
1:40.8	Dr. Dayspring goes without saying thank you again for coming back to tag on another podcast
1:47.1	episode addressing listeners questions of which we got hundreds, not surprisingly, hoping that we
1:53.6	could dive into some of these topics and a little bit greater detail for the listening community.
1:59.6	Well, that makes me happy because if you're getting that many questions, people are listening
2:03.9	and they're thinking, and they're interested in these topics. So I'm happy to continue to share
2:09.6	knowledge with you. Yeah, one of my son's mother's friends actually has a chemistry degree,
2:15.4	and she said, what I loved about the first series we did together
	...

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