Ep. 521 Metabolism Masterclass: Weight Loss Resistance Explained with Cynthia Thurlow, NP

Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Cynthia Thurlow

Alternative Health, Nutrition, Science, Life Sciences, Health & Fitness

4.8 • 1K Ratings

🗓️ 19 November 2025

⏱️ 72 minutes

🔗️ Recording | iTunes | RSS

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Summary

Today, we have the first episode in a two-part mashup series focused on metabolism and weight loss resistance. I am delighted to be joined today by Dr. William Li, Michelle Shapiro, and Lara Adler. Dr. Li and I explore how our metabolism shifts throughout our lifetime, the role of excess body fat, the influence of lifestyle choices, and the distinction between different types of fat. Michelle and I discuss the complex relationship between weight, shame, and self-perception, including how internal dialogue, orthorexia, and adverse childhood events shape our health journey. Lara and I examine how metabolic health and insulin resistance are affected by the endocrine-disrupting chemicals found in everyday products, food, and the environment. You will love this invaluable compilation, packed with insights and practical knowledge from our expert guests. IN THIS EPISODE, YOU WILL LEARN: How metabolism changes as we age The difference between brown (biologically active) and white fat Excess body fat drives inflammation and hormonal changes. How our internal dialogue influences our lifestyle choices Impact of adverse childhood experiences on long-term health and stress responses Dietary strategies can fail when driven by fear or perfectionism. Endocrine-disrupting chemicals block or mimic hormones Early-life chemical exposures set the stage for lifelong metabolic challenges Reducing toxic exposure can support weight management and metabolic resilience. How reducing your exposure to endocrine-disrupting chemicals present in everyday products can support your metabolic health and help you manage your weight Connect with Cynthia Thurlow Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to [email protected] Connect with Dr. William Li On social media: @Dr William Li On his website Sign up for Dr. Li’s free newsletter Ep. 354 Metabolism Myths Debunked: Weight Gain Insights with Dr. William Li Connect with Michelle Shapiro On her website Quiet the Diet Podcast Ep. 390 Understanding Shame, Food Behaviors & Weight Loss with Michelle Shapiro Connect with Lara Adler On her website On Facebook and Instagram Ep. 159 Lara Adler Explains The Link Between Chemical Exposure And Weight Gain & Other Health Issues

Transcript

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0:00.0	Welcome to Everyday Wellness Podcast.
0:03.7	I'm your host, nurse practitioner, Cynthia Thurlow.
0:07.4	This podcast is designed to educate, empower, and inspire you to achieve your health and wellness goals.
0:13.9	My goal and intent is to provide you with the best content and conversations from leaders in the health and wellness industry each week and impact
0:22.1	over a million lives.
0:29.1	This is the first in a series of mashup podcast episodes devoted to metabolism and weight loss
0:36.9	resistance.
0:40.4	I am joined in this episode by Dr.
0:47.6	William Lee, Michelle Shapiro, and Lara Adler. Dr. Lee and I discuss how metabolism changes throughout our lifetime, the role of excess body fat, the impact of lifestyle and choices
0:53.5	governing our health, as well as what differentiates
0:57.5	biologically active fat. Michelle and I dove into the impact of weight, weight gain and loss
1:04.2	and shame, and our internal dialogues that are critically important for not only our perception
1:09.6	of self, but how we view lifestyle
1:12.1	changes. The impact of orthorexia as well as adverse childhood events. And lastly, Lara Adler
1:18.7	and I dive into the impact of metabolic health and insulin resistance and how endocrine disrupting
1:24.3	chemicals and our personal care product, food, and environment can impact our ability
1:28.9	to lose weight or to shift our body composition. I know you will find this to be an invaluable
1:34.8	compilation of three guest experts on the podcast. But I love the fact we're still discovering
1:44.1	things.
1:44.5	Okay, there's a researcher at Duke University named Herman Ponzer who worked with 90 other colleagues from 20 countries.
1:51.2	And they wanted to ask a question.
1:52.5	They said, what does human metabolism look like over the course of a lifetime?
	...

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