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Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Ep. 504 The Pill Changes Your Brain – The Shocking Truth About Birth Control & Mental Health with Dr. Sarah Hill

Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Cynthia Thurlow

Alternative Health, Nutrition, Science, Life Sciences, Health & Fitness

4.81K Ratings

🗓️ 27 September 2025

⏱️ 68 minutes

🧾️ Download transcript

Summary

Today, I am thrilled to be joined by Dr. Sarah Hill, an award-winning researcher, professor, and leading voice in the field of women’s hormones and brain health. She wrote This Is Your Brain on Birth Control and has also authored The Period Brain, which is due to be released this fall. In our conversation, Dr. Hill dispels the myths surrounding bioidentical hormones and shares her view on how women are not biologically disordered, but just ignored by science. We dive into research on how oral contraceptives affect the brain and how the pill creates a dysregulated stress response, particularly in women with histories of adverse childhood experiences. We also explore progesterone through the lens of an evolutionary biologist and neuro-endocrinologist, highlighting its role in supporting GABAergic tone, the key differences between synthetic progestins and natural progesterone, and research on PMS and PMDD, including practical ways to manage those issues. This helpful discussion with Dr. Sarah Hill is a must-listen for women at every stage of life. IN THIS EPISODE, YOU WILL LEARN: Why has science ignored women? How oral contraceptives affect the way women perceive the world How early-life trauma impacts the ability to manage stress in adulthood Often-overlooked benefits of progesterone The different ways estrogen and progesterone impact women’s ability to build muscle mass from resistance training The positive effects of the GABAergic system in the brain The problem with combined hormone therapy How progesterone gets ignored and villainized, even though it can help women experience better lives How the protective and anti-inflammatory properties of progesterone support brain health and enhance neuroplasticity What the research suggests for women experiencing severe PMS or PMDD Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to [email protected] Connect with Dr. Sarah Hill On her website Instagram Pre-order a copy of Dr. Hill’s new book, The Period Brain: The New Science of Why We PMS and How to Fix It, which will be on sale at the end of September.

Transcript

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0:00.0

Welcome to Everyday Wellness Podcast.

0:03.7

I'm your host, nurse practitioner, Cynthia Thurlow.

0:07.4

This podcast is designed to educate, empower, and inspire you to achieve your health and wellness goals.

0:13.9

My goal and intent is to provide you with the best content and conversations from leaders in the health and wellness industry each week and

0:21.5

impact over a million lives.

0:29.1

Today, I had the honor of connecting with Sarah Hill, an award-winning researcher,

0:34.2

professor, and thought leader in the area of women's hormones and the brain.

0:38.0

She is also the author of This Is Your Brain on Birth Control and the period brain that is due

0:44.2

out later this fall. Today we spoke at length about how women are not disordered, we're just

0:50.4

ignored by science, the impact of oral contraceptives on brain health, as well as relevant

0:57.1

research, how the pill creates an abnormal stress response, especially in the setting of

1:03.6

adverse childhood events, the significance of progesterone, as well as a perspective from

1:09.4

an evolutionary biologist and neuroendocrinology.

1:13.6

Why gababurgic tone is so important?

1:18.6

Why progestins are not akin to progesterone and relevant research.

1:23.6

The impact of PMS and PMDD and ways to proactively assess it, excuse me, and

1:31.4

proactively address it. This is a truly invaluable conversation, a favorite of 2025

1:37.7

discussion, something that is relevant to all women, irrespective of life stage.

1:45.3

There's a quote that really stood out to me because it resonated with me both as a woman

1:49.9

who was once in those peak fertile years, now as a menopausal female.

1:55.1

And the quote is, women aren't disordered.

1:58.2

We're just ignored by science.

...

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