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Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Ep. 501 Is Your Thyroid Medication Failing You? – The Most Overlooked Fixes for Energy, Weight & Mood with McCall McPherson, PA-C

Everyday Wellness: Midlife Hormones, Menopause, and Science for Women 35+

Cynthia Thurlow

Alternative Health, Nutrition, Science, Life Sciences, Health & Fitness

4.81K Ratings

🗓️ 17 September 2025

⏱️ 66 minutes

🧾️ Download transcript

Summary

Today, we have the first episode of a series of AMAs with McCall McPherson. McCall McPherson is the visionary behind Modern Thyroid Clinic, a thyroid-centered functional medicine practice in Austin, Texas. McCall is a physician assistant and thyroid expert. She is a recent TEDx speaker, a frequent guest on podcasts and summits, and the owner, host, and Chief Thyroid Hope Giver of the Thyroid Nations podcast.  Today, McCall joins me to dive into a range of listener questions, covering whether intermittent fasting damages the thyroid, the role of GLP-1s, constipation, split-dosing medication, adrenal health, ADHD, phentermine versus Glucophage versus GLP-1s, and how HRT affects thyroid medication. We also explore the impact of lipids on thyroid health and the role of nutrition, and we share our opinions on the Dutch test.  This invaluable AMA was made even more special by the flood of questions submitted by listeners. IN THIS EPISODE, YOU WILL LEARN: The benefits of adopting a nuanced approach to intermittent fasting  How Graves' disease and Hashimoto's differ in terms of fasting Why fasting is not advisable when taking GLP-1s Do thyroid medications cause constipation? Strategies for overcoming constipation and improving gut health McCall shares her rationale for splitting thyroid medication doses Will progesterone increase free T4 levels? The importance of rechecking thyroid labs after starting or adjusting HRT Foods to avoid and include in your diet for thyroid health Is the Dutch test worth using? Connect with Cynthia Thurlow   Follow on X, Instagram & LinkedIn Check out Cynthia’s website Submit your questions to [email protected] Connect with McCall McPherson Modern Thyroid Clinic  Modern Weight Loss On Instagram and TikTok Modern Thyroid and Wellness Podcast

Transcript

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0:00.0

Welcome to Everyday Wellness Podcast.

0:03.7

I'm your host, nurse practitioner, Cynthia Thurlow.

0:07.4

This podcast is designed to educate, empower, and inspire you to achieve your health and wellness goals.

0:13.9

My goal and intent is to provide you with the best content and conversations from leaders in the health and wellness industry each week and impact

0:22.1

over a million lives.

0:28.9

Today I had the honor of reconnecting with friend and colleague McCall McPherson.

0:33.8

She's the visionary behind modern thyroid clinic, a thyroid-centered functional medicine

0:39.1

practice in Austin, Texas. The now owner and chief thyroid hope giver of Thyroid Nation,

0:44.9

a frequent podcast and summit guest and now host of Thyroid Nation's podcast. She's a physician assistant,

0:50.9

recent TEDx speaker, and thyroid expert. Today, graciouslyiously mccall join me again to go over

0:57.4

listeners questions that ran the gamut from does intermittent fasting hurt my thyroid the role of

1:04.2

glp ones the impact of constipation split dosing medication, ADHD, phantramine versus glucophage versus

1:15.6

gulp-1s, how HRT impacts thyroid medication, the impact thyroid health and lipids, and the role of

1:25.5

nutrition. And lastly, our take on the Dutch test. This is a truly

1:30.8

invaluable experience, one that was made extra special because so many of you submitted questions.

1:36.6

Obviously, I will need to bring McCall back multiple times to get through all of them. But

1:41.2

today is the first of a series of AMAs with McCall.

1:48.0

McCall, thank you for carving time out of your busy schedule to meet again. Our podcast that we did a few weeks ago was so popular and you very graciously said, hey, if we're getting a lot of questions, let's do and ask me anything. And we were truly

2:03.1

overwhelmed with questions. I had to pair them down. Otherwise, you and I would be talking for

2:06.7

hours and hours, which of course would be a joy for me. But we have personal lives that we have

2:10.8

to get to. So welcome back to the podcast. Thank you so much. I will always come anytime I'm

2:16.8

invited. This is one of my favorite things to do.

...

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