Ep 310 - Are People Getting "Metabolic Stress" Wrong?

Iron Culture presented by MASS

The MASS Crew

Health & Fitness

4.8 • 874 Ratings

🗓️ 15 January 2025

⏱️ 93 minutes

🔗️ Recording | iTunes | RSS

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Summary

In today's episode, Drs Trexler and Helms discuss a wide range of fitness topics including metabolic stress, "the pump," targeting the different heads of the biceps, individualising diets and supplement protocols, maximal rates of fat loss, blood flow restricted training, the philosophy of science, and much more!

We had some technical issues while recording this episode live, but it's all fixed now with the wonders of editing. If you don't understand a couple of the jokes, they're referring to chaos that has been deleted.

Time stamps:

00:00 Straight into the topic: why should anyone care about metabolic stress?
03:13 Helms takes a deep dive into energy systems and muscle physiology
12:37 Subjective and objective measures of the pump and potential influencing factors
22:12 Arterial and venous occlusion
29:35 Update on Trexler's training and Q&A 1 different curl variations
38:53 Q&A 2 Manipulating forearm position for the biceps?
42:42 Q&A 3 Can BFR increase vascularity? And an aside on muscle memory and testosterone
48:03 Q&A 4 Individualising supplements and diet
58:34 Q&A 5 Fat oxidation and maximum rate of fat loss per day with some applications for contest prep
1:13:42 Q&A 6 Science communicators/educators and the philosophy of science
Larsen 2025 Knee flexion range of motion does not influence muscle hypertrophy of the quadriceps femoris during leg press training in resistance-trained individuals https://sportrxiv.org/index.php/server/preprint/view/502
Kubo 2019 Effects of squat training with different depths on lower limb muscle volumes https://pubmed.ncbi.nlm.nih.gov/31230110/
Iron Culture Ep. 109- Empiricism vs Rationalism: What Do We Really Know When It Comes To Fitness? https://www.youtube.com/watch?v=qT3KPnTgO7M
1:29:27 Q&A 7 Using BFR in practice
1:30:50 Closing out
MASS Research Review https://massresearchreview.com/

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Transcript

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0:00.0	Hey, everybody. Welcome back to a flawless night. It's Monday 7 p.m., not 716. We're doing Iron Culture presented by Mass, and I'm here with a good Dr. Eric Holmes. And Dr. Eric Holmes, I've heard, I have it on good authority that you've been thinking a lot lately about metabolic stress.
0:24.2	I have.
0:24.8	Was it fair to say that it's frankly stressing you out a bit?
0:29.1	You know what?
0:31.4	I feel like it's requiring a lot of oxygen from me, but that I'm getting through it without it.
0:36.2	You know, so.
0:41.4	So metabolic stress, I mean, what in the world?
0:43.9	First of all, why do you care?
0:45.5	And second of all, should I?
0:47.8	And third of all, should the listener?
0:50.9	I think that is a great way of framing it.
0:56.1	Well, I will say that given our audience, I would suspect that a lot of people have encountered the term metabolic stress in the context of it being one of those big three
1:02.1	mechanisms for hypergraphy that the good doctor, uh, Schoenfeld has proposed way back when in 2010.
1:09.9	And, um, it's been repeated since then. Like, hey, so metabolic
1:13.7	stress is either causes hypertrophy, maybe independently. Drop to C word, which is big in research.
1:23.4	I know. Or maybe it has an additive effect on other on to hypertrophy, or maybe it just indirectly can impact hypertrophy, or some would claim it has no influence at all on hypertrophy.
1:38.0	But let me ask you this, Trex, how often when you hear people in kind of the evidence-based sphere talking about metabolic stress, do you think that they really know what they're saying when they say metabolic stress?
1:50.7	What percent?
1:51.2	Fifteen percent of the time.
1:53.5	I think that's pretty accurate.
1:55.2	I would have been okay with anywhere from 12 to 18 percent.
1:59.0	Oh, good.
	...

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