4.8 • 17.1K Ratings
🗓️ 28 May 2019
⏱️ 60 minutes
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This week's episode comes with a warning: don't attempt this at home. While self-experimentation has led to many a scientific breakthrough, we're definitely not advocating it. But it happened to work out for the best for Barry Marshall and Robin Warren, even earning them a Nobel prize. That’s right folks, today we’re talking about none other than Helicobacter pylori, the curvy little bacterium identified only a few decades ago to be a causative agent of peptic ulcer disease, a major risk factor in the development of gastric cancer, and a fierce warrior who can survive the harshest of environments: your stomach.
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0:00.0 | This is exactly right. |
0:07.1 | I decided that I was going to have to drink the bacteria myself. |
0:10.5 | I thought I would just be having no symptoms for a few years, after which I would have an |
0:14.6 | ulcer. |
0:15.6 | And then, hallelujah, it'd be proven. |
0:17.9 | Actually, I was very shy about this experiment. |
0:20.6 | I didn't tell anyone, not even my wife or Robin, until afterwards. |
0:24.8 | I asked my boss in gastroenterology, Ian Hislop, to do an endoscopy for me one day. |
0:30.2 | As he put the scope down, he was saying, Barry, I'm not going to ask why I'm doing this. |
0:34.8 | And from around the tubing, I gritted out, just take the biopsy. |
0:38.6 | So he took some biopsies from me, and they were all clear. |
0:41.6 | No bacteria. |
0:43.2 | Then I infected myself with bacteria that I'd cultured from a patient who did not actually |
0:48.1 | have ulcers, just indigestion and gastritis. |
0:51.3 | I was able to eradicate his infection with some antibiotics. |
0:54.8 | So already I knew that I could, if necessary, take a treatment which worked on this bug. |
1:00.3 | I had some safety features built in, I thought. |
1:03.0 | I drank the bacteria, and at first I was okay. |
1:06.2 | But instead of being perfectly well and having a silent infection, after about five days, |
1:10.9 | I started having vomiting attacks. |
1:13.3 | Typically, at dawn, I would wake up, run to the toilet, and vomit. |
1:17.7 | And it was a clear liquid, as if you had drunk a pint of water and regurgitated it straight |
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