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This Podcast Will Kill You

Ep 29 Aspirin the Wonder Drug: Crossover w/ IDOP

This Podcast Will Kill You

Exactly Right and iHeartPodcasts

Health & Fitness, Science

4.817.1K Ratings

🗓️ 11 June 2019

⏱️ 79 minutes

🧾️ Download transcript

Summary

On this very special crossover episode with our friend Matt Candeias from In Defense of Plants, we’re switching things up from poison to remedy, focusing on the plant-derived wonder drug, aspirin! We cover the ancient use of salicylic acid-containing willow bark to relieve pain and fevers and then reveal how such a harsh compound was transformed into a useable pharmaceutical. We also delve into what happens in your body when you pop an aspirin and discuss why on earth so many plants make this incredible compound. Spoiler - it’s not just a wonder drug for humans. See Privacy Policy at https://art19.com/privacy and California Privacy Notice at https://art19.com/privacy#do-not-sell-my-info.

Transcript

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0:00.0

This is exactly right.

0:30.0

Hi, I'm Erin Welsh. And I'm Erin Owen of Dake. And I'm Matt. Yes. Yes. And this is this podcast will kill you.

0:52.0

Cross-over style with... In defensive plants. Yes. And this week, even though our past episodes have primarily focused on poisons, we're doing something a little bit different.

1:07.0

A little bit healthier? I mean, it could be a poison if you took enough of it. Well, that's true. I mean, that was the lesson we learned in poisons, I guess.

1:17.0

Yeah. But this week we are talking all about aspirin. And in particular, willow and some of the other plants that produce some of the primary components that are made are that are used to make aspirin.

1:31.0

Yeah. This was an exciting one because it's something that I was introduced to early on when I was starting to learn about plants. And something we all kind of took advantage of and a shout out to my friend who started putting willow bark in his tea and then realized he was bruising really bad.

1:46.0

There was a steep learning curve when we figured out that this was around. Wow. So this is a this is like a harkening back to my early days of plant obsessiveness.

1:56.0

You're like first flirtation with plants. Yeah. Yeah. How fun. Cool. Wow. Okay. So to celebrate aspirin, we are drinking our quarantini named pain in the aspirin. Yeah. There we go. Excellent.

2:15.0

And what is in pain in the aspirin? We've got rum lemon juice and time simple syrup. It's really delicious. Keep it as simple. It's quite tasty.

2:28.0

Some good botanical families in there. Yeah. Yeah. And we will we'll post the recipe for this quarantine as well as the non alcoholic placebo Rita on all of our social media plate pages, including Twitter, TPWKY and Facebook and Instagram. This podcast will kill you.

2:44.0

And our website this podcast will kill you dot com. So I'm I'm really excited about the history of aspirin because it reaches back so much farther than I thought. And it also has associations or connections with a lot of other things that we have already talked about in different areas of the podcast. So be excited. All right.

3:14.0

So this week we're talking about aspirin and because this is a crossover with you, Matt, we're not just talking about aspirin, but also the plant it comes from, which is the willow and some of the other species of plants.

3:40.0

And let me tell you willow and humans go way way back. In fact, they go so far back that we can't even say for certain when people started using willow bark as medicine or if it was even homo sapiens that used it first.

3:58.0

Oh, because willow bark was actually found in a Neanderthal burial site in Iraq dating back to 60,000 BCE.

4:08.0

Are you serious? Yes, we can't and we don't know for sure. Obviously, or people don't know for sure why it was there, whether it was included intentionally or had been used for, I don't know, some sort of ritualistic purpose.

4:20.0

Or maybe it was just a random toss some, you know, things in there. Super cool. So what do historical texts tell us something called the or you are third three. I don't know tablet.

4:36.0

I read it. It's cool. It's fine.

4:38.0

Oh, yeah. The earth is done. The earth three. This tablet dates back to 3000 BCE from ancient Sumeria and it includes some of the earliest known references to willow as a treatment.

4:50.0

And you probably or maybe not remember me talking about the ebers, Ebers papyrus. Yeah, just that yeah, that medical text from ancient Egypt.

5:00.0

And it was written around 1534 BCE, but it contained information that was much, much older. So some sections had been copied from documents that were at least a thousand years older.

5:13.0

Wow. Jesus.

5:14.0

And Egyptologists have gone through the over 160 remedies listed in this papyrus to try to identify the ingredients.

...

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