Today, I’m happy to welcome Dr. John Lieurance as my guest! Dr. Lieurance is a doctor of chiropractic and naturopathic medicine and the author of Melatonin: Miracle Molecule (Melatoninbook.com). Melatonin is a very misunderstood hormone that is astonishingly impactful. It has profound, significant, and far-reaching effects that go all the way to the cellular level. Most of us are shocked to hear the story of the connection between melatonin, inflammation, infections, and mitochondrial health and discover that much of what we do in our modern-day lives harms our melatonin production. In this episode, Dr. Lieurance and I dive into the role of melatonin plays in stress protection, anti-aging, and brain function. We talk about hormesis, discuss what depletes melatonin, and explain why those who are sympathetic dominant in our modern-day lifestyles need to be highly attuned to this crucial hormone. We get into the role of sleep, the role of deep sleep in brain health, autophagy, and autoimmunity. We touch on the gut microbiome and explain why specific populations, including shift workers, should be concerned about supporting melatonin secretion. We also discuss the role of SandMan and other products Dr. Lieurance created, including Fast Track Fast, which contains Nad, Methylene Blue, and other senolytic products. IN THIS EPISODE YOU WILL LEARN: Dr. Lieurance explains the connection between the body’s adaptation response to stressors and disease. What part does melatonin play in how the mitochondria in our cells respond to inflammation? Repleting lost reserves of melatonin can be helpful, provided you make some lifestyle changes. Dr. Lieurance explains the difference between pineal melatonin and extra-pineal melatonin. Key things that cause disease in our modern civilization. Dr. Lieurance explains why he refers to melatonin as “the ultimate resilience molecule” and recommends supplementing it later in life. Studies have proven that melatonin supplementation is non-toxic. (Using a high-quality product is vital, however.) Getting enough sleep is crucial for good health. Dr. Lieurance discusses the glymphatic system, what it does, and various things that could affect it. Dr. Lieurance talks about his Fast Track Fasting program. Why should you take melatonin after a fast? How does melatonin benefit the gut microbiome? Dr. Lieurance explains the effectiveness of suppositories as a delivery system for melatonin supplementation. What can shift workers do to support their bodies and prevent metabolic disease? Some changes you can make to your home and bedroom to protect your sleep. Taking melatonin internally and externally is an effective hack for healthy skin. Bio: Dr. John A. Lieurance is a Doctor of Chiropractic, Naturopath (no license in FL), Registered Medical Assistant, and Performs Musculoskeletal Ultrasound. He has practiced in Sarasota for 24 years. Dr. Lieurance is a regular guest on many media outlets, has been on the Documentary “Pain Revealed”, and is a contributor for both ABC 7 news, and SNN news, as well as on popular podcasts like Ben Greenfield Fitness and CellTV with Dr. Dan Pompa. Dr. Lieurance is the developer of Functional Cranial Release and teaches, as well as certifies, these methods to doctors around the world. He is the author of Melatonin: Miracle Molecule see Melatoninbook.com. Connect with Cynthia Thurlow Follow on Twitter, Instagram & LinkedIn Check out Cynthia’s website Connect with Dr. John Lieurance On his website: MitoZen Scientific or Advanced Rejuvenation Instagram: Dr John Lieurance (@doctormitozen) • Instagram photos and videos Dr. John Lieurance’s book, Melatonin: Miracle Molecule SandMan™ Glutathione & Melatonin Bullet) Monthly Subscription (For 5% off, use code Cynthia.) Fast Track Fasting program John Lieurance | Facebook Instagram: Dr John Lieurance (@doctormitozen)