Ep 205 Cancer Part 4: Where do things stand today?
This Podcast Will Kill You
Exactly Right and iHeartPodcasts
4.8 • 17.7K Ratings
🗓️ 31 March 2026
⏱️ 80 minutes
🧾️ Download transcript
Summary
For the entirety of our species’ history, our approach to cancer has largely been to react, to design new therapies and better combinations of treatments. This energy has certainly been well-spent, but what if we didn’t have to use treatment at all? Or what if we could minimize the use of aggressive therapies? Prevention and screening represent two under-appreciated pillars of cancer care, and we’re using this final installment in our cancer miniseries to show some appreciation. To grasp the impact that screening and prevention can have, we also need to consider the global landscape of cancer prevalence and incidence - where is it decreasing? Where is it on the rise? Where can intervention or prevention make an impact? As we’ve shown over these four episodes, science and medicine has accumulated a wealth of information about cancer - but the striking racial and socioeconomic disparities in cancer incidence and mortality in the US and around the world demonstrates that that knowledge has not been applied equally. Any proposal to reduce the global cancer burden must address the systemic issues driving these disparities. Tune in for a thought-provoking reflection on the status of cancer today.
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Transcript
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| 0:00.0 | This is exactly right. |
| 0:05.9 | Throughout this series, we'll be discussing many aspects of cancer diagnosis and treatment, |
| 0:11.4 | and we will be sharing several personal stories related to cancer. |
| 0:15.0 | Some listeners might find this content upsetting. |
| 0:17.9 | Please listen with discretion. |
| 0:22.8 | My name is Christina, and I'm a healthy, |
| 0:27.4 | cancer-free, 30-year-old woman who is about to undergo a double mastectomy. Let me tell you why. |
| 0:32.9 | My aunt Helen was diagnosed with breast cancer at age 34 and ultimately passed away 10 years later when I was 13. Just a few years later, still reeling from the loss of our beloved Helen, another aunt was diagnosed with ovarian cancer. My whole life I had looked at my aunts and saw myself, all blue eyes and big foreheads and curly hair. If their fate was cancer, it was bound to be mine too. And it wasn't just my aunts. Six other relatives from great aunts to distant cousins had been diagnosed with either |
| 0:54.2 | breast or ovarian cancer. It was high time for genetic testing, and we discovered that my aunt and |
| 0:58.8 | father carry the Broca 2 mutation. This mutation is associated with a 40 to 85% lifetime risk for |
| 1:04.7 | breast cancer and a 15 to 40% risk for ovarian cancer, along with increased risks for other cancers, |
| 1:10.5 | including prostate, pancreatic, and melan increased risks for other cancers, including prostate, |
| 1:11.4 | pancreatic, and melanomas. As a teenager, I wanted to be tested immediately. This was around when |
| 1:17.2 | the Affordable Care Act was being passed, and my doctors recommended that I wait until protections |
| 1:21.1 | for preexisting conditions were fully in effect before diagnosing myself with one. Finally, at 19, |
| 1:26.9 | I received confirmation of what I had felt for years. |
| 1:29.3 | Just like my aunts, I was positive for Rocca 2. |
| 1:32.3 | I heard constantly at the time that 19 was too young to test, years before any screenings would be recommended. |
| 1:37.3 | But I wanted those years to sit with my diagnosis and process it as slowly as I wanted to. |
| 1:42.3 | I'm so grateful for the protections that allowed me to do so. |
| 1:46.3 | My cancer screenings began at 24, and for six years, I've dutifully scheduled breast exam, |
| 1:51.1 | skin checks, and an annual date was a clunking, thumping MRI. I'm treated by an excellent hereditary |
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