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The Human Upgrade: Biohacking for Longevity & Performance

Empathy: the Unexpected Key to Transforming Lives, Drew Manning : 534

The Human Upgrade: Biohacking for Longevity & Performance

Dave Asprey

Nutrition, Fitness, Wellness, Fasting, Lifestyle, Meditation, Science, Brain, Hacking, Self-improvement, Fat, Biohacking, Health & Fitness, Education, Diet

4.67.4K Ratings

🗓️ 11 October 2018

⏱️ 58 minutes

🧾️ Download transcript

Summary

Drew Manning is the author of the New York Times best-selling book Fit2Fat2Fit: The Unexpected Lessons From Gaining And Losing 75 Lbs On Purpose. In this episode, we talk about Drew’s winding journey of fitness, faith, failure and feats of self-awareness. 

He’s best known for his year-long Fit2Fat2Fit.com experiment that went viral, garnered national attention, and led to appearances on Dr. Oz, Good Morning America, The View and more. His experiment also became a hit TV show called “Fit to Fat to Fit,” and aired on the A&E and Lifetime channels.

In the 7 years since that experiment, Drew has helped thousands of people learn to live a healthy lifestyle and transform their lives.

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Transcript

Click on a timestamp to play from that location

0:00.0

You're listening to Bulletproof Radio with Dave Asprey.

0:15.8

Today's cool fact of the day is that human genes are getting a recount.

0:20.4

It turns out that figuring out how many genes are in our human genetic instruction manual,

0:25.9

the human genome isn't as easy as we once thought.

0:29.5

In fact, the definition of a gene has changed since they completed the human genome project

0:34.5

more than 15 years ago.

0:36.9

And we used to identify genes as stretches of DNA that had instructions that get copied

0:40.8

into RNA and turned into proteins.

0:43.3

But researchers still don't really agree on how many of those genes there are.

0:48.0

They range from 19,901 to 21,306.

0:54.2

And in the last decade, they realized that not all genes produce proteins.

0:58.4

So some scientists have expanded the definition of a gene to include genes that make RNAs

1:03.6

that don't turn into proteins but turn into other things.

1:06.7

So the number of those RNA-producing genes, which they call non-coding genes, is even

1:12.5

more up in the air than the protein-coding genes, according to Johns Hopkins University.

1:17.7

And it turns out there's about 25,000 of those RNA genes that they didn't think about.

1:22.7

So when someone tells you, oh, that's written into your genetic code, well, between this

1:29.2

fact that the genetic code is a bit blurry, and the fact that we have epigenetics, which

1:33.6

is how the environment turns genes on and off, well, the future isn't set in stone, at

1:39.5

least not genetically, at least not most of the time.

1:44.1

And the new total of human genes that's come out from all this research is about 46,831,

1:53.6

but not everyone agrees.

...

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