E175 - Dr. Will Bulsiewicz: How Stress, Trauma, and Modern Life Break Your Gut & How To Restore Balance
Know Thyself
André Duqum
4.8 • 658 Ratings
🗓️ 9 December 2025
⏱️ 93 minutes
🧾️ Download transcript
Summary
In this episode, Dr. Will Bulsiewicz walks us through unseen forces shaping our health, energy, and emotional lives. From the chemicals in our food system to the hidden drivers of inflammation and burnout, we dive into why so many people today feel exhausted, misaligned, and disconnected from their true well-being.
We examine how modern culture normalizes habits and environments that work against our biology, and why healing requires more than symptom management — it demands addressing the root causes, rebuilding alignment, and taking ownership of what we allow into our bodies and minds.
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00:00 Intro: Will Bulsiewicz
02:34 How much of our mood is controlled by our gut?
09:40 Two diseases: individualism and materialism
23:30 The intelligence that lives in our gut
35:31 Ad: Pique Life
36:46 What is immune intelligence?
48:01 Detoxing from environmental toxins
54:54 Why are chemical companies allowed to poison us?
57:39 A short horror story
1:02:45 Looking out for what to avoid
1:05:27 The effects of factory farming on our bodies
1:17:36 Humans are the microbes of the Earth
1:26:23 Conclusion: Changing the world
___________
Episode Resources:
https://www.amazon.com/Plant-Powered-Plus-Activate-Inflammation/dp/0593418794
https://www.instagram.com/theguthealthmd/
https://theguthealthmd.com/
https://www.instagram.com/andreduqum/
https://www.instagram.com/knowthyself/
https://www.youtube.com/@knowthyselfpodcast
https://www.knowthyselfpodcast.com
Transcript
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| 0:00.0 | Three out of five people ultimately will die from inflammatory health conditions. So that means |
| 0:04.8 | like we're playing a silly game when we're addressing symptoms without actually getting to the source of |
| 0:10.1 | our problems. And it turns out that we're all a bit silly when we make it sound like nutrition is the only |
| 0:15.3 | thing that matters because there is so much more. I have discovered that our mood is clearly impacted by our gut in several |
| 0:22.4 | powerful ways. Where do you think is the most effective place to start to guard what's coming in? |
| 0:27.9 | That way we don't have to try to heal what could be prevented. Like it's actually quite simple. |
| 0:32.9 | Here's an example, and I did not know this. 80% of the chemicals, and there's 10,000 of them now and climbing, have never had a feeding study on a human or an animal. So we're speculating that they're safe? Like, that's the extent of what we're doing here? So here's the interesting thing. We're going to play a little game. I will list the ingredients in a commonly used product, and you will guess what it is. Here we go. |
| 0:55.5 | Need I say more? |
| 0:56.4 | It's insane. |
| 0:57.0 | It's disturbing. |
| 1:03.9 | Hey, everyone. |
| 1:05.8 | Welcome back to the Know of Myself podcast. |
| 1:10.7 | Our guest today is a leading gastroenterologist, a gut health expert, a New York Times best-selling author, |
| 1:11.9 | somebody that I loved having a conversation with last time. His work has been mentioned over |
| 1:17.6 | 5,000 times by other researchers, and it's by no wonder because he's an incredible articulator |
| 1:23.3 | of very important messaging around gut health, around the immune system, and how to increase |
| 1:30.9 | vitality as a human being in general. Dr. Will Bolswoods, thank you for coming back. |
| 1:34.9 | Thank you, Andre. It's good to be here. |
| 1:37.0 | If somebody who's listening to this episode right now is asking themselves, as they often may |
| 1:42.0 | do, what is the most meaningful shift I could have by the end of |
| 1:47.1 | this conversation? What can I look forward to the promise of this conversation why people |
| 1:50.9 | should be tuning in? Honestly, I'm going to say to you the exact same thing that I wrote in the |
... |
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