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Low Carb MD Podcast

Dopamine, Serotonin, and the Keto Diet | Dr. Rubén Ancona Bolaños - E410

Low Carb MD Podcast

Drs. Brian Lenzkes & Tro Kalayjian

Medicine, Mental Health, Health & Fitness

4.81.2K Ratings

🗓️ 15 September 2025

⏱️ 76 minutes

🧾️ Download transcript

Summary

Dr. Rubén Ancona Bolaños is a Metabolic Health Practitioner from Mexico who has been having incredible success using ketogenic therapies to help his patients reclaim their metabolic health! He has a special interest in the interplay between diet, metabolic health, and hormones like dopamine and serotonin.
 
From this episode…
 
"One of my hypotheses is that insulin resistance could start at a young age — with dopamine resistance in the brain's reward center."
 
"We need to stop seeing the body and the brain as separate—hormones affect the brain, and neurotransmitters affect the body."
 
"Kids today are constantly hyper-stimulated, always releasing dopamine, which desensitizes their brain's reward system and raises their threshold for feeling pleasure."
 

In this episode, Drs. Tro and Rubén talk about…

  • (00:00) Intro
  • (02:02) How Dr. Rubén first became interested in metabolic health
  • (22:07) How addiction plays into metabolic dysfunction
  • (27:07) How Dr. Rubén helps his patients reclaim their metabolic health
  • (29:05) Dopamine, serotonin, oxytocin, and insulin resistance
  • (53:39) Gut health and antibiotics
  • (56:47) Dopamine detoxing
  • (01:03:29) Dr. Rubén's clinical approach
  • (01:08:50) How to keep patients motivated

For more information, please see the links below. Thank you for listening!

 

Links:

 

Please consider supporting us on Patreon: https://www.lowcarbmd.com/

 

Dr. Rubén Ancona Bolaños:

 

Dr. Brian Lenzkes: 

 

Dr. Tro Kalayjian: 

 

Toward Health App

Join a growing community of individuals who are improving their metabolic health; together. 

Get started at your own pace with a self-guided curriculum developed by Dr. Tro and his care team, community chat, weekly meetings, courses, challenges, message boards and more. 

 

Apple: https://apps.apple.com/us/app/doctor-tro/id1588693888 

Google: https://play.google.com/store/apps/details?id=uk.co.disciplemedia.doctortro&hl=en_US&gl=US

Learn more: https://doctortro.com/community/ 

Transcript

Click on a timestamp to play from that location

0:00.0

Welcome to the Low Carb MD Podcast.

0:03.0

No one is beyond help.

0:05.0

No one is beyond hope.

0:07.0

Nothing said on the Low Carb MD podcast is medical advice.

0:11.0

Please consult your own doctor before making any lifestyle changes.

0:20.0

You know, Brian got to this amazing guest before I had a chance to, and we struggled to connect.

0:28.8

But finally, you know, fate has put us together.

0:32.3

We have Dr. Rubin and Konak Bologna, who is a MD and also a researcher in Mexico.

0:42.0

We've met several times, I think at least once, once at Boka, maybe twice at Boka.

0:48.1

And it's, you know, I heard him a couple months back on, I thought it was a little bit further back,

0:55.3

but he told me three months ago on the Life's Best Medicine podcast, and we're excited to have him on today.

1:04.1

We were just talking about some of his thesis work, looking at exogenous ketones versus ketosis.

1:11.4

So I'm excited to talk about that.

1:13.5

And I'm certainly excited to talk about the fact that we need to,

1:17.2

and I know this is something our mutual friend,

1:21.1

Dr. Adrian Sotomoto has been working on,

1:23.1

but sort of revitalizing the or vitalizing the metabolic movement in South America, Central America.

1:33.3

They revitalize the movement because there's so many brilliant lines in Central Mexico, first and foremost,

1:43.3

but all throughout Central and South America.

1:48.3

So how can we amazing conferences that happen that people don't even know about with

1:54.3

thousands of people in Chile?

1:57.5

And so how can we unite these continents a little bit? So I'm excited to talk about that.

...

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