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The Rich Roll Podcast

Does The Microbiome Hold The Key To Treating Parkinson’s, Autism & Other Diseases? CalTech Microbiologist Dr. Sarkis Mazmazian on The Gut-Brain Axis

The Rich Roll Podcast

Rich Roll

Health & Fitness, Education, Self-improvement, Society & Culture

4.812.9K Ratings

🗓️ 9 May 2024

⏱️ 136 minutes

🧾️ Download transcript

Summary

This week, I am joined by microbiologist Dr. Sarkis Mazmanian, the Luis B. and Nelly Soux Professor at Caltech, to discuss the microbiome's connection to human health—especially the gut-brain axis. Dr. Mazmanian discusses his research evolution from infectious diseases to the microbiome’s role in neurodevelopment and neurodegeneration, as well as how gut microbes influence neurological health, behavior, and conditions like Parkinson's, autism, and depression. He highlights the human gut microbe symbiosis, early-life microbial exposure's influence, and the adult microbiome's malleability. We explore microbiome-based therapeutics' potential, challenges in translating animal models to humans, personalized medicine's future, the microbiome's impact on drug efficacy, gut bacteria's influence on behaviors and cravings, and the importance of a healthy gut diet. Please enjoy! Show notes + MORE Watch on YouTube Newsletter Sign-Up Today’s Sponsors: AG1: Get a FREE 1-year supply of Vitamin D3+K2 AND 5 free AG1 Travel Packs 👉drinkAG1.com/richroll InsideTracker: Use code RICHROLL at checkout and enjoy 10% OFF the InsideTracker Subscription and any plan 👉insidetracker.com/richroll On: 10% OFF your first order of high-performance shoes and apparel w/ code RICHROLL10👉on.com/richroll Roka: Unlock 20% OFF sunglasses & eyewear with code RICHROLL 👉roka.com/richroll Go Brewing: Use the code Rich Roll for 15% OFF my favorite non-alcoholic brews 👉gobrewing.com Squarespace: Use the offer code RichRoll to save 10% off your first purchase of a website or domain 👉Squarespace.com/RichRoll

Transcript

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0:00.0

I own a bunch of spectacles and I made the grave error the other day of

0:05.1

donning a normal non-Roca pair on my indoor trainer when I was riding my bike

0:10.9

indoors and I got to tell you it was a disaster.

0:14.6

Every three to five seconds I had to take my hands off the handlebars and push my glasses

0:20.0

back up my nose until I got so frustrated I just tossed him aside. This is the

0:26.3

dilemma of every active but optically impaired person I know and as someone who has

0:32.4

relied upon I wear every single day since I was five years old,

0:35.3

it is also the source of endless aggravation. Thankfully, now eradicated, thanks to Brokka, the stylish performance eyewear company founded by two former

0:46.8

Stanford swimming teammates of mine who have gifted everyone like me and quite frankly the world with their fashionable line of super lightweight prescription

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glasses and sunglasses with patented no slip nose and temple pads that are just impervious to sweat and no matter what you do

1:06.0

from being locked on your load no matter how intense your workout.

1:10.1

Without the dork factor, these things go everywhere with me from the trail to the dinner

1:15.0

park. Put them on, feel the difference, and wear the value of the credits.

1:19.7

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1:25.0

That's R-O-K-A.com.

1:27.0

We're brought to you today by a very exciting brand new sponsor, Go Brewing.

1:38.0

I am sober. I don't drink and I devoted so many episodes of this podcast to the unreal benefits of an

1:47.4

alcohol-free lifestyle. Why? Because even if you don't have issues with booze and suds, no amount of alcohol is good for you.

1:56.5

At a minimum, it wreaks havoc on your sleep and produces a hangover that destroys your

2:01.1

energy, your mood, and your focus.

2:03.0

At worst, it turns your whole life upside down.

2:06.0

But no longer does that mean you have to break up with your favorite brew

...

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