Dinakar Singh - A Father’s Call To Action - [Invest Like the Best, EP.428]

Invest Like the Best with Patrick O'Shaughnessy

Colossus

Investing, Business, Technology

4.8 • 2.4K Ratings

🗓️ 15 June 2025

⏱️ 49 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

My guest today is Dinakar Singh. Dinakar is the founder and CEO of Axon, the family office successor to TPG-Axon, which was a successful global long-short hedge fund. We wanted to share his story on Father’s Day to honor the person and the dad that Dinakar is. He shares one of the most extraordinary stories at the intersection of finance and medicine I've ever encountered. This conversation explores the highest-stakes investment themes—timing, concentrated conviction, exceptional team building, and deploying resources toward outcomes that matter most. I will let him tell you his story. Please enjoy my conversation with Dinakar Singh. For the full show notes, transcript, and links to mentioned content, check out the episode page⁠⁠⁠ here.⁠⁠⁠ ----- This episode is brought to you by⁠⁠⁠ Ramp⁠⁠⁠. Ramp’s mission is to help companies manage their spend in a way that reduces expenses and frees up time for teams to work on more valuable projects. Go to⁠⁠⁠ Ramp.com/invest⁠⁠⁠ to sign up for free and get a $250 welcome bonus. – This episode is brought to you by⁠⁠⁠ Ridgeline⁠⁠⁠. Ridgeline has built a complete, real-time, modern operating system for investment managers. It handles trading, portfolio management, compliance, customer reporting, and much more through an all-in-one real-time cloud platform. Head to⁠⁠⁠ ridgelineapps.com⁠⁠⁠ to learn more about the platform. – This episode is brought to you by⁠⁠⁠ AlphaSense⁠⁠⁠. AlphaSense has completely transformed the research process with cutting-edge AI technology and a vast collection of top-tier, reliable business content. Invest Like the Best listeners can get a free trial now at⁠⁠⁠ Alpha-Sense.com/Invest⁠⁠⁠ and experience firsthand how AlphaSense and Tegus help you make smarter decisions faster. ----- Editing and post-production work for this episode was provided by The Podcast Consultant (⁠⁠⁠https://thepodcastconsultant.com⁠⁠⁠). Show Notes: (00:00:00) Welcome to Invest Like the Best (00:06:17) The Diagnosis and Initial Reactions (00:07:29) Understanding SMA and the Scientific Challenge (00:09:15) The Drive to Fund Research and Find a Cure (00:14:10) Building a Virtual Company for Drug Development (00:19:02) Breakthroughs and the First Approved Drugs (00:24:16) Personal Reflections and the Impact of the Journey (00:40:25) Challenges in the Biotech Industry and Future Hopes (00:46:43) The Kindest Thing Anyone Has Ever Done For Dinakar

Transcript

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0:00.0	Something I speak about frequently on Invest Like the Best is the idea of life's work.
0:04.5	A more fun way to think about it is that I'm looking for maniacs on a mission.
0:08.5	This is the basis for our investment firm, Positive Sum, and it's the reason why I'm so enthusiastic about our presenting sponsor, Ramp.
0:15.0	Not only are the founders, Karim and Eric, life's work-level founders, certainly maniacs on a mission.
0:20.0	They have created a product that is effectively an unlock for founders and finance team to do more of their life's work
0:25.5	by streamlining financial operations, saving everyone their most precious resource time.
0:30.9	Ramp has built a command and control system for corporate cards and expense management.
0:35.1	You can issue cards, manage approvals, make vendor payments of all kinds, and even automate
0:39.4	closing your books all in one place.
0:41.7	Speaking from my own experience using Ramp for my business, the product is wildly intuitive,
0:46.4	simplistic, and makes life so much easier that you'll feel bad for any company who hasn't
0:50.4	yet made the switch.
0:52.5	The Ramp team is relentless, and the product continues to evolve to save you time
0:56.0	that you would never have dreamed of getting back.
0:58.2	To me, there is nothing more interesting
1:00.0	than technologies that reduce friction for other entrepreneurs
1:03.7	to be able to build the thing that they want to.
1:06.2	So much attention has gone to cloud computing,
1:08.8	APIs, and other ways of making life easy for founders,
1:12.5	what RAMP has done and is doing is build yet another set of tools in this category.
1:18.0	To get started, go to ramp.com.
1:20.5	Cards issued by Celtic Bank and Sutton Bank, member FDIC, terms and conditions apply.
	...

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