Debunking Health Myths: Digging into the Truth About LDL Cholesterol, Heart Disease, & Keto Diet with Dave Feldman

Dhru Purohit Show

Dhru Purohit

Alternative Health, Medicine, Health & Fitness

4.7 • 3.6K Ratings

🗓️ 4 March 2024

⏱️ 107 minutes

🔗️ Recording | iTunes | RSS

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Summary

The current thoughts around LDL cholesterol center on the fact that there is no scenario in which high LDL numbers could occur in healthy individuals. Traditionally, the belief is high levels of LDL can lead to a greater risk of cardiovascular disease regardless of metabolic health. Today’s guest is here to share his hypothesis and research on how higher cholesterol levels in metabolically fit individuals could be a physiological response rather than a pathological response that can lead to disease. Today on The Dhru Purohit Show, Dhru sits down with Dave Feldman to discuss high levels of LDL in metabolically healthy individuals. Dave shares the current research on high LDL and cardiovascular disease in individuals eating a ketogenic diet. He also shares his personal approach to focusing on metabolic health and the key markers critical to overall health. Dave discusses the process and findings of the Oreo experiment conducted by his colleague and explains why this experiment further proves their hypothesis on how LDL particles move through the body. Dave Feldman is a software and platform engineer, entrepreneur, and founder of the Citizen Science Foundation. Through a series of self-experiments and partnering with formal researchers, he has since published the "Lipid Energy Model," which may explain this phenomenon. In this episode, Dhru and Dave dive into (audio version / Apple Subscriber version): Dave’s hypothesis on LDL (00:24 /00:24) Rethinking our approach to high LDL (2:17 / 2:17) The research on high LDL and cardiovascular disease (10:00 / 6:48) The Oreo experiment and what it shows about fat adaptation (17:23 / 13:45) The pushback to lean mass hyper responder (27:36 / 24:15) Soft plaque versus hard plaque and the risk of cardiovascular disease (37:50 / 35:04) Dave’s personal approach in focusing on overall metabolic health (51:42 / 48:30) Fasting Insulin and Vitamin D (59:33 / 53:45) Endothelial health and cardiovascular health (1:03:28 / 57:45) The vegan’s twin study and the correlation to LDL (1:21:17 / 1:15:49) Dhru’s experience (1:32:17 / 1:26:36) Also mentioned in this episode: Citizen Science Foundation Oreo Cookie Treatment Nicolas Norwitz, PhD Twitter This episode is brought to you by LMNT, Momentous, and Lumebox. Right now, LMNT is offering my listeners a free sample pack with any purchase. Head over to DrinkLMNT.com/dhru today. Optimize your Omega-3 levels by choosing a quality fish oil made by and used by the best. Go to livemomentous.com and enter promo code DHRU to get 20% off any order. Lumebox is offering my community $260 off their FDA-approved portable Red Light device! That's over 50% off! Go to thelumebox.com/dhru and get your Red Light device. Hosted on Acast. See acast.com/privacy for more information. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0	Dave, welcome to the podcast a pleasure to have you here. You know you have a pretty wild and
0:05.9	somewhat shocking to some people hypothesis around LDL and. Cholesterol. One that if proven to be true could have the scientific community rethink the nuances around
0:20.0	L. D. L. cholesterol and it's linked to heart disease.
0:22.6	So I'd love to start there.
0:24.2	If you wouldn't mind sharing, what is this hypothesis?
0:28.6	Well, cholesterol that is, you know, being picked up in a blood test is often associated with
0:36.0	cardiovascular disease and that's why it's assumed that generally speaking the lower
0:41.1	you can get it the better and the more likely it is that you'll have
0:44.8	less heart disease and what happened to me is I went on a low-carb diet my
0:48.8	cholesterol went up substantially but I myself I have no background in formal research.
0:56.4	I'm actually a software engineer and was building platforms and code.
1:00.5	But when this happened to me and my cholesterol went up, I had that fear that the cholesterol levels for as high as they were,
1:07.0	were going to lead me down the road of cardiovascular disease.
1:10.0	And spoiler alert, I don't have a straight answer for that just yet.
1:14.0	We'll kind of get a chance to go into how we're getting that information.
1:18.0	But yes, the hypothesis is the exact scenario I'm describing where I myself who tend to be leaner and more
1:25.9	metabolically healthy and saw my cholesterol go up from going on a ketogenic diet and becoming
1:32.3	adapted to consuming fat, that actually the higher level of
1:36.1	cholesterol may be physiological as opposed to pathological.
1:41.3	I know there's two big words,
1:43.3	but physiological meaning,
1:44.8	it may actually be a normal process
	...

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