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The Diary Of A CEO with Steven Bartlett

David Sinclair: Can Aging Be Reversed? After 8 Weeks, Cells Appeared 75% Younger In Tests!

The Diary Of A CEO with Steven Bartlett

FlightStory

Education, Society & Culture, Business

4.517.8K Ratings

🗓️ 23 March 2026

⏱️ 150 minutes

🧾️ Download transcript

Summary

Scientist and Harvard professor Dr. David Sinclair, A.O., Ph.D., reveals his latest research on how to reverse ageing, insights into vitamins and supplements, why DNA is not your destiny, and the first clinical trials to reverse human ageing and blindness! Dr. David Sinclair is a world-renowned Professor of Genetics at Harvard Medical School and the leading authority on longevity science. He is Founder of Lifespan.com and multiple biotechnology companies, Co-Chief Editor of the journal Ageing, and bestselling author of ‘Lifespan: Why We Age - And Why We Don’t Have To’.  Dr. Sinclair explains:  ◼️The “Information Theory of Aging” that regards ageing as a treatable disease  ◼️Advances in resetting biological age using cellular “backup copies”  ◼️His specific supplement stack for longevity ◼️Why fasting and “good stress” are science-based longevity strategies  ◼️How his lab’s gene therapy is being used to restore eyesight and reverse blindness  Enjoyed the episode? Share this link and earn points for every referral - redeem them for exclusive prizes: https://doac-perks.com  Research document: https://docs.google.com/document/u/0/d/1sarDR85LvkK5hv7HMN_UUDvHO9MIi9bNPhLyIRZQ9vg/edit Follow David: Lifespan - https://lifespan.com/  Instagram - https://linkly.link/2ajhU  Podcast - https://linkly.link/2aji0  YouTube - https://link.thediaryofaceo.com/AiIza5B  The Sinclair Lab - https://linkly.link/2ajhX  You can purchase David’s book, ‘Lifespan: Why We Age-and Why We Don't Have To’, here: https://linkly.link/2ajhc  The Diary Of A CEO: ◼️Join DOAC circle here - https://doaccircle.com/  ◼️Buy The Diary Of A CEO book here - https://smarturl.it/DOACbook  ◼️The 1% Diary is back - limited time only: https://bit.ly/3YFbJbt  ◼️The Diary Of A CEO Conversation Cards (Second Edition): https://g2ul0.app.link/f31dsUttKKb  ◼️Get email updates - https://bit.ly/diary-of-a-ceo-yt  ◼️Follow Steven - https://g2ul0.app.link/gnGqL4IsKKb  Sponsors: Bon Charge: https://boncharge.com/DOAC for 20% off Shopify - https://shopify.com/bartlett  Ketone - https://ketone.com/STEVEN for 30% off your subscription order

Transcript

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0:00.0

One thing I've learned from interviewing a lot of founders and building companies myself is that

0:03.5

trust is the real currency of business. It's the thing that gets customers to buy, partners to say yes,

0:08.5

and investors to back you. But as you grow, trust stops being just a feeling and becomes something

0:13.1

you have to prove. Because the bigger you get, the more exposed you are, customer data,

0:17.4

security expectations, regulations, all of it. And the risk of one small mistake

0:21.1

becomes incredibly significant. And if you've ever tried to scale while keeping on top of all of that,

0:26.6

you'll know it can become a full-time job. But our sponsor Vanta automates your compliance

0:31.3

processes and brings compliance, risk and customer trust together through their AI-powered platform.

0:36.8

And the company's already using Vanta, say they spend 82% less time on audits because of Vantas platform.

0:43.1

So if your organization wants to inject time back into building and growing, make sure you head over to vanta.com slash diary.

0:49.7

That's vanta.com slash diary.

0:53.0

This is very... It's bad, right?

0:55.9

It's hard, yeah.

0:56.6

That's what it's like to be old.

0:58.0

And for far too long, we've ignored it or accepted it as natural.

1:01.6

And I reject the idea that aging, just because it's natural, is acceptable.

1:05.6

Dying at 80 is not inevitable.

1:08.0

Absolutely, that can be changed.

1:09.6

So if you're skeptical, I am a Harvard professor who has been studying aging longevity and age reversal for 30 years. And I've seen enough from my lab showing that we can literally now reverse the aging process. And it's not a question of if, it's a question of when this is going to happen. And everyone should stick around because I'm going to tell you some of the major things that people should be doing.

1:29.1

They can lengthen your life by a decade.

1:48.2

Hey, you're not taking that off, Steve. Oh, yeah. You got 10 minutes of that. So you can accelerate aging by smoking. Getting an X-ray, ultra-processed foods, excessive drinking, flying a lot. I fly all the time. That's probably accelerating your aging process. even going to a rock concert and blasting your eardrums because your ear hair cells are getting older faster.

1:49.2

And so I look at the body like it's a computer and we can reinstall the software.

...

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