Cryopreservation, Personality Transplant, Fungal Azoles
Curiosity Weekly
Warner Bros. Discovery
4.6 • 963 Ratings
🗓️ 22 August 2024
⏱️ 13 minutes
🧾️ Download transcript
Summary
Today, you’ll learn about a new method to cryopreserve parts of the brain for later use, the personality changes that happen after organ transplants, and how fungicides cause dangerous fungi to self-destruct.
Cryopreservation
- “Effective cryopreservation of human brain tissue and neural organoids.” by Weiwei Xue, et al. 2024.
- “Brain organoids: Establishment and application.” by Hao Chen, et al. 2022.
Personality Transplant
- “Personality Changes Associated with Organ Transplants.” by Brian Carter, et al. 2024.
- https://www.mdpi.com/2673-3943/5/1/2
- “Does changing the heart mean changing personality? A retrospective inquiry on 47 heart transplant patients.” by B Bunzel, et al. 1992.
- https://pubmed.ncbi.nlm.nih.gov/1299456/
Fungal Azoles
- “Azoles activate type I and type II programmed cell death pathways in crop pathogenic fungi.” by Martin Schuster, et al. 2024.
- https://www.nature.com/articles/s41467-024-48157-9
- “Leaf Blotch Disease of Wheat - Septoria tritici Blotch, Stagonospora nodorum Blotch and Tan Spot.” by Jorge David Selgado & Pierce A. Paul. 2016.
- https://ohioline.osu.edu/factsheet/plpath-cer-07
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| 0:00.0 | So, so, so skin. |
| 0:02.0 | Get your morning mojo going with woolen-like Greek style. |
| 0:08.0 | Now with a new recipe, with Vitamin B-6 and Vitamin D. Let's have it! |
| 0:16.0 | Mull-a-light, get the good going. Hello and welcome to Curiosity Daily from Discovery. My favorite place to get smarter in just a few minutes. Thanks for joining us. I'm Nate. |
| 0:33.5 | How the heck are you guys? We are so excited to have you here with us today. |
| 0:36.5 | My name is Callie. |
| 0:37.5 | Today you'll learn about a new method to cryopreserve parts of the brain for later use, the personality changes that happen after organ |
| 0:45.0 | transplants, and how fungicides cause dangerous fungi to self-destruct. |
| 0:50.2 | All right, let's get smarter. Researchers have found a new way to effectively cryopreserve brain tissue. |
| 0:56.7 | Wow, okay, so this is every sci-fi lover's dream come true. |
| 1:00.0 | Is this a way to basically freeze our brains and then I don't know wake them up in some |
| 1:04.0 | distant future? So no not that not that exactly this is no less revolutionary but for a very |
| 1:11.9 | different reason and it all comes down to something |
| 1:14.5 | called brain organoids. Okay if I remember correctly organoids are kind of like |
| 1:19.7 | models. Yeah you're on the right track for sure. So any neuroscientists studying anything having to do with brain function will at some point need brain organoids. |
| 1:29.0 | Generally, these are models derived from human stem cells that can kind of mimic aspects of brain development. |
| 1:35.0 | Sometimes they're called mini brains and one of the coolest things about them is that they are 3D. |
| 1:40.4 | Okay, wait, isn't all tissue 3D? Well, technically, yeah, but no. So most animal |
| 1:47.8 | models or cell cultures are basically two-dimensional. Think about them |
| 1:51.6 | resting peacefully and flatly on say a microscope slide. |
| 1:56.0 | Oh, okay, right. Using mini brains or organoids opens up huge opportunities in the research of things like brain development and |
| 2:04.4 | neurodevelopmental disorders like autism or schizophrenia. |
... |
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