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Science Weekly

Could faecal transplants be the next frontier in health?

Science Weekly

The Guardian

Science

4.21K Ratings

🗓️ 28 March 2023

⏱️ 16 minutes

🧾️ Download transcript

Summary

Madeleine Finlay hears from science correspondent Linda Geddes about her experience becoming a faecal transplant donor, how getting a dose of someone else’s gut bacteria could treat illnesses like arthritis, diabetes and cancer, and asks whether a pill made from poo is an idea we are ready to swallow. Help support our independent journalism at theguardian.com/sciencepod

Transcript

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0:00.0

This is the Guardian.

0:10.0

So I'm heading into Central London on the tube carrying what looks very like a kind of

0:16.4

Tupperware style soup container.

0:20.3

That's Guardian Science Correspondent Linda Gedis, talking about a trip she recently took across London.

0:26.7

And then I get out of the tube at Westminster and cross Westminster Bridge, which is very busy actually, and I'm kind of watching my step because again I don't want to trip up and risk

0:38.1

dropping this container on the floor that would be an absolute disaster.

0:42.4

And why would spilling her cargo be so bad? Well,

0:47.1

inside that box is a freshly laid poo. That's all that's a very healthy, a very special, poo of mine. The reason I was carrying my poo across London was that I had

1:07.5

volunteered as a fecal transplant donor. Researchers are exploring the potential of fecal transplants,

1:16.0

inserting poo through the rectum into the colon,

1:19.0

to treat all kinds of gut-related conditions.

1:22.0

But the reason I was at St Thomas's is because they

1:26.2

have been working on a different way of getting the bacteria from healthy donors

1:30.8

into people's guts and that's through capsules or

1:34.8

crapsules as they're known in the trade.

1:39.5

The hope is that these crapsules could one day be prescribed for a whole range of diseases.

1:45.0

But is this something people are ready to swallow?

1:49.0

From the Guardian, I Mad Madeline Finley, and this is Science Weekly.

1:57.0

Linda Gedes, you're a science correspondent for The Guardian and recently you reported on and contributed to the science of fecal transplants, so in a way that we can easily digest, what is a fecal transplant?

2:18.4

A fecal transplant involves taking bacteria or sometimes poo from a healthy person and getting them into the

2:28.0

guts of somebody who is suffering from usually an infection with a bug called Clostridium difficile.

2:37.6

That's the kind of only licensed use at the moment, but fecal transplants are currently being explored in all sorts of clinical trials around the world

...

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