Hey, all, welcome back to the real-life pharmacology podcast.

I'm your host, pharmacist, Eric Christensen.

Thank you so much for listening today.

As always, go check out our free 31-page PDF on the top 200 drugs.

It's a great study guide, great review if you're out in practice.

Simply an email is going to get you access to that.

So kind of a no-brainer to go get that

at real-life pharmacology.com. The drug of the day today is going to be clindamysin. I'm kind of

surprised, honestly. I haven't done this one yet, but I appreciate the podcast listener that reached out and said, hey, cover this

antibiotic.

So that's what we're going to do.

Brand name in this medication is Cleosin.

And this is classified as a lincosomide antibiotic.

I know there's temptation for those of you who are maybe new to pharmacology

to lump clindamysin in with the macrolide antibiotics, but it is not.

So again, the macrolides like Clarithromycin, erythromycin,

they are different from clindomycin for sure.

So mechanistically, how does this drug work?

It binds to the 50s ribosomal subunit, which ultimately blocks bacterial protein synthesis.

And if bacteria can't produce proteins and continue to function normally,

obviously that's going to lead to bacteria's death.

Indications.

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