Claude Opus 4.5, White House "Genesis Mission" & Amazon's $50B AI Push w/ Emad Mostaque, Salim Ismail, Dave Blundin & Alexander Wissner-Gross | EP #211
Moonshots with Peter Diamandis
PHD Ventures
4.8 • 605 Ratings
🗓️ 26 November 2025
⏱️ 88 minutes
🔗️ Recording | iTunes | RSS
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| 0:00.0 | I've compared this moment to 1939. |
| 0:03.0 | This is the Manhattan Project. |
| 0:05.0 | Similar to the Apollo project that put a man on the moon in 1969. |
| 0:09.0 | This is an all-in national effort to take the power of AI to use the world's largest supercomputers to advance innovation and science. |
| 0:19.0 | This is just extraordinary. I think this could be the greatest |
| 0:23.1 | accelerator for human knowledge in the US yet if it's properly funded and executed. Genesis 1 is |
| 0:30.2 | God created the heavens and the earth. Finally, we have the tools to be actually able to understand |
| 0:34.4 | them properly. Application of large amounts of compute with the reagents allows us to unravel |
| 0:38.9 | the mysteries of the Earth and the universe. |
| 0:40.9 | You know, if we went back to the beginning of the year, |
| 0:43.1 | did we predict that we'd be here |
| 0:44.8 | or is it moving faster than even the few of us could predict? |
| 0:53.9 | Now that's a moonshot, ladies and gentlemen. |
| 0:58.7 | Hey guys, welcome to our emergency pod for Thanksgiving week. |
| 1:03.1 | A lot going on here. |
| 1:05.5 | Genesis mission, we're going to be talking about that. |
| 1:07.5 | We'll talk about Anthropics, U-Claude 4.5. |
| 1:16.5 | I'm here with AWG, Mr. EXO, and thank you, |
| 1:20.5 | Imod, for joining us. I know this is Thanksgiving for you in England as well, isn't it? |
| 1:27.2 | It's Thanksgiving for everyone. Ah, yes, for sure. So I wanted to start with a question, which is, what does Thanksgiving look like in the year 2035? I'm curious. Is it going to change it all? |
| 1:32.7 | Saleem, you want to kick it off? Is 2035 far enough a way to make a difference? |
| 1:38.1 | It's a hell of a difference. I mean, look, by that point, we should have the cost of Thanksgiving dinner dropping by 10x. |
... |
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