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Moonshots with Peter Diamandis

Claude Opus 4.5, White House "Genesis Mission" & Amazon's $50B AI Push w/ Emad Mostaque, Salim Ismail, Dave Blundin & Alexander Wissner-Gross | EP #211

Moonshots with Peter Diamandis

PHD Ventures

Business

4.8 • 605 Ratings

🗓️ 26 November 2025

⏱️ 88 minutes

🧾️ Download transcript

Summary

If you want us to build a MOONSHOT Summit, email my team: moonshots@diamandis.com  Get access to metatrends 10+ years before anyone else - https://qr.diamandis.com/metatrends   Emad Mostaque is the founder of Intelligent Internet ( https://www.ii.inc )  Read Emad’s Book: https://thelasteconomy.com  Salim Ismail is the founder of OpenExO Dave Blundin is the founder & GP of Link Ventures Dr. Alexander Wissner-Gross is a computer scientist and founder of Reified – My companies: Apply to Dave's and my new fund:https://qr.diamandis.com/linkventureslanding      Go to Blitzy to book a free demo and start building today: https://qr.diamandis.com/blitzy   Grab dinner with MOONSHOT listeners: https://moonshots.dnnr.io/ _ Connect with Peter: X Instagram Connect with Emad:  Read Emad’s Book X  Learn about Intelligent Internet   Connect with Dave: X LinkedIn Connect with Salim: X Join Salim's Workshop to build your ExO  Connect with Alex Website LinkedIn X Email Listen to MOONSHOTS: Apple YouTube – *Recorded on November 25th, 2025 *The views expressed by me and all guests are personal opinions and do not constitute Financial, Medical, or Legal advice. Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

I've compared this moment to 1939.

0:03.0

This is the Manhattan Project.

0:05.0

Similar to the Apollo project that put a man on the moon in 1969.

0:09.0

This is an all-in national effort to take the power of AI to use the world's largest supercomputers to advance innovation and science.

0:19.0

This is just extraordinary. I think this could be the greatest

0:23.1

accelerator for human knowledge in the US yet if it's properly funded and executed. Genesis 1 is

0:30.2

God created the heavens and the earth. Finally, we have the tools to be actually able to understand

0:34.4

them properly. Application of large amounts of compute with the reagents allows us to unravel

0:38.9

the mysteries of the Earth and the universe.

0:40.9

You know, if we went back to the beginning of the year,

0:43.1

did we predict that we'd be here

0:44.8

or is it moving faster than even the few of us could predict?

0:53.9

Now that's a moonshot, ladies and gentlemen.

0:58.7

Hey guys, welcome to our emergency pod for Thanksgiving week.

1:03.1

A lot going on here.

1:05.5

Genesis mission, we're going to be talking about that.

1:07.5

We'll talk about Anthropics, U-Claude 4.5.

1:16.5

I'm here with AWG, Mr. EXO, and thank you,

1:20.5

Imod, for joining us. I know this is Thanksgiving for you in England as well, isn't it?

1:27.2

It's Thanksgiving for everyone. Ah, yes, for sure. So I wanted to start with a question, which is, what does Thanksgiving look like in the year 2035? I'm curious. Is it going to change it all?

1:32.7

Saleem, you want to kick it off? Is 2035 far enough a way to make a difference?

1:38.1

It's a hell of a difference. I mean, look, by that point, we should have the cost of Thanksgiving dinner dropping by 10x.

...

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