Hey all, welcome back to the Real Life Pharmacology podcast. I'm your host, pharmacist,

Derek Christensen, and I thank you so much for listening today. As always, go check out

real life pharmacology.com. Get that free 31-page PDF. No-brainer simply for subscribing to the

podcast. Simple email. We'll get you access to that PDF. Great review if you're out of practice or if you're preparing for any board exams or going

through pharmacology classes in schools.

So again, real-life pharmacology.com.

Go get that free 31-page PDF on the top 200 drugs.

Great little study guide.

All right, so let's get into the drug of the day today, and that is chlorthalodone.

And this is going to be a little bit more interesting in that we've had some recent research done on chlorthalodone.

And I'll get to that a little bit, but some of the basics, brand name is thalitone.

This drug is classified as a thiozide diuretic.

So similar to hydrochlorothiozide, metolazone,

those are some of the other drugs that are going to have similar effects

to a drug like

chlorthalidone. So you can imagine its uses are going to be pretty similar to that as well.

In practice, hypertension is by far the most common use that I've seen this medication used for,

followed by probably edema swelling.

Again, we often go more towards the loop diuretics like ferrosamide for removal of fluid,

but thiaside diuretics can have that effect as well.

And then lastly, on a rare occasion, I have seen it utilized for the prevention of calcium-based renal stones because chlorthalodone actually helps retain calcium back into the body.

And so that prevents it from going out and contributing to growing stones and that type of

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