Butyrate — The Metabolic Powerhouse Fueling the Gut and Beyond

Dr. Joseph Mercola - Take Control of Your Health

Briana Mercola

Health & Fitness, Alternative Health

4.6 • 1.5K Ratings

🗓️ 23 December 2025

⏱️ 8 minutes

🔗️ Recording | iTunes | RSS

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Summary

Avoidant restrictive food intake disorder (ARFID) is an eating disorder where people severely restrict food due to fear, sensory sensitivities, or low interest — not body image concerns — causing significant health and social problems
Unlike normal picky eating, ARFID involves intense distress, extremely narrow food choices, nutritional deficiencies, weight loss, and serious disruption to daily life and social activities
Prevalence ranges from 0.35% to 6.4% depending on region, primarily affecting children and teens, with average diagnosis at age 11 and higher male representation than other disorders
Treatment approaches include parental control strategies, cognitive behavioral therapy, family-based treatment, food therapy, and sequential oral sensory methods to gradually reduce food-related fear and anxiety
A specialized protocol combining psychology, hypnosis, and neuro-linguistic programming shows 90% success for adults and 65% for children, often achieved in single session

Transcript

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0:00.0	What if the fuel your gut prefers could also steady your glucose, reduce inflammation, and help you manage weight?
0:07.0	Welcome to Dr. Mercola's cellular wisdom. Stay informed with quick, easy-to-listen summaries of our latest articles, perfect for when you're on the go.
0:15.0	No reading required. Subscribe for free at Mercola.com for the latest health insights.
0:20.0	Hello, and welcome to Dr. Mercola's cellular wisdom.
0:24.6	Today we're examining Beauty Rate, the short chain fatty acid your gut bacteria make
0:29.8	when you ferment fiber, and how it supports your metabolism, your gut barrier, and your
0:35.3	overall energy.
0:36.7	I'm Ethan Foster. You'll hear how beauty rate improves
0:39.7	insulin function, regulates glucose, and supports healthy body composition, and why your colon cells
0:46.5	rely on it more than glucose. I'm Alara Sky. We'll also outline when boosting fiber helps,
0:53.4	when it backfires, and a stepwise way to
0:56.0	rebuild gut tolerance so you can actually benefit from butyrate production.
1:01.0	Buterate stands out among short chain fatty acids because research links it to better body weight
1:07.1	and composition, improved lipid profiles, stronger insulin sensitivity, and steadier
1:12.5	glycemia. It acts through gene pathways influenced by histone diacetylase inhibition, and by activating
1:19.5	free fatty acid receptors in tissues like intestine, adipose, muscle, liver, pancreatic islets, and blood vessels.
1:28.3	Your colonocytes prefer butyrate as their main fuel.
1:32.3	They bring it across the cell membrane by diffusion and active transport,
1:36.3	shuttle it to mitochondria, and convert it via beta oxidation into acetyl co-A to generate ATP. That single pathway can supply roughly 70% to 80% of their energy needs,
1:50.0	far more than they tend to draw from glucose or glutamine.
1:54.0	When your colonocytes oxidize butyrate efficiently, they also lower oxygen levels in the colon.
2:00.0	That shift favors beneficial anaerobic oxygen levels in the colon. That shift favors beneficial
	...

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