Briefing chat: ‘Can it run Doom?’ — why scientists got brain cells and a satellite to play the classic game
Nature Podcast
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4.5 • 893 Ratings
🗓️ 13 March 2026
⏱️ 11 minutes
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Summary
00:26 Why researchers keep using Doom in their research
Nature: How the classic computer game Doom became a tool for science
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| 0:00.0 | Hi listeners, Benjamin here. Welcome to The Nature Briefing podcast, the Friday show where we talk about a few things we've read about in the nature briefing. |
| 0:13.0 | We've got one quick story today, and we're back in the world of video games. |
| 0:18.3 | Now, specifically, a historically important entry to the medium, and that is |
| 0:23.8 | Doom, released in 1993 by ID Software. It's a first-person shooter that will be familiar to many |
| 0:31.4 | of you listening right now. Perhaps like me, even if you've not played it in many years, |
| 0:36.1 | the cheat code IDKFA is seared into your brain. |
| 0:41.2 | But this isn't a trip down memory lane today. Doom has become something of a workhorse of science. |
| 0:48.6 | And writing about this is Nature's Rachel Fieldhouse, who joins me down the line from Australia. |
| 0:53.5 | Rachel, thank you so much |
| 0:54.5 | for being here today. Thanks for having me. And I say there it's a workhorse. It's been used as a tool |
| 0:58.8 | across many scientific disciplines, right? Absolutely. Everything from computer science and AI all the way to |
| 1:05.8 | biology. And there's a particular subculture that I have been fascinated about for years, which I think perhaps is the main thrust of your article. And this is this can it play doom, almost meme, I guess. Now, basically if something has a screen, people will try and get it to run doom. |
| 1:23.1 | Essentially, yeah. We've seen everything from calculators and smart fridges to even computerized pregnancy tests and the little digital bars on the top of MacBook keyboards. |
| 1:33.5 | It's glorious, right? I mean, you and I have been showing them. I think electric toothbrush is one of my favorites. |
| 1:37.5 | Getting Doom to play inside of Doom is a recursive nightmare. We haven't got time to talk about. But there are hundreds of them, and listeners can go and find |
| 1:44.6 | them on the internet, and many of them are glaringly silly. But there's a new one that's been |
| 1:49.9 | added to the list that you've really been taking a look at. Yes, so a team in Australia have |
| 1:55.3 | decided to essentially get their biological computer to run Doom. So their computer is basically a collection of about 200,000 neurons on top of a silicon |
| 2:04.9 | chip. |
| 2:05.9 | And so what they've done is they worked with this independent researcher from Singapore, who |
| 2:11.6 | wrote the code, and it was part of a hackathon that they ran. |
| 2:16.0 | And the whole point of the challenge was, can people get Doom to run on their biological computer? |
... |
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