Hello, I'm Greg Jenna and good news, Your Dead to Me is back for a new series. Here we go. Yes, we'll explore Emperor Nero's notorious reign with Professor Marybeard and Patton Oswald. I would not want my daughter having the remote control, not alone an empire. We'll dissect the decadent life of Philippe Duke-Dor-Leon with Tom Allen. I've often tried to pretend I'm an aristocrat and being very quickly knocked down. And there'll be so much more with comedians like Olga Koch, Mike Mosniak and Ria Lina. I'm excited. You're dead to me, the comedy podcast that takes history seriously. Listen first on BBC Sounds. Hello, I'm Dr Mark Porter and thank you for downloading this edition of Inside Health.

I hope you enjoy it.

Hello, coming up in today's program, getting the most out of your workouts.

We examine the science behind pulse rate monitors, side effects and how to be sure a particular medicine is causing them.

Margaret McCartney explains the rationale behind taking a drug holiday and medicines for children,

why there's growing concern about how little is being spent on research and development

into treating childhood illnesses. At the moment in the UK, we spend less than £10 per child on research,

which isn't very much really compared to the amount of money which is spent on research

in adults, which is then trying to deal with the diseases which probably had their origins

in childhood to start off with. But first, breast cancer, a new guidance from America, suggesting

that women at increased risk of developing the disease should be offered estrogen-blocking

drugs like tamoxifen to protect them.

A move that's being mirrored here in the UK

by the National Institute for Health and Care Excellence,

Nice, which is currently putting the finishing touches to a very similar initiative.

But what constitutes high risk?

Well, in the States, doctors use an online questionnaire-based

calculator, with women deemed as having a 3% or more risk of developing breast cancer over

the next five years, being those most likely to benefit from the drugs. As an example,

any woman over 45 with two close relatives with a disease is likely to have at least a 3% risk.

To explain more about the American proposals, I'm joined on Skype from Athens, Georgia by Dr. Mark Abel, an epidemiologist at the US

Preventive Service Task Force. Women can consult an online breast cancer risk tool and use that

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