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The Root Cause Medicine Podcast

Breaking Down the New GLP-1 Advisory with Lara Zakaria, IFMCP

The Root Cause Medicine Podcast

Kate Kresge

Health & Fitness, Alternative Health, 810564, Medicine

4.8 • 581 Ratings

🗓️ 2 October 2025

⏱️ 58 minutes

🧾️ Download transcript

Summary

This episode of The Root Cause Medicine Podcast explores how the 2025 GLP-1 prescribing advisory from the American College of Lifestyle Medicine, the American Society for Nutrition, the Obesity Medicine Association, and The Obesity Society can act as a catalyst for whole-person metabolic care—rather than just symptom management. Lara Zakaria, IFMCP, pharmacist and functional medicine practitioner, breaks down the new consensus guidelines and highlights opportunities to integrate nutrition counseling, strength training, and lab monitoring to support muscle preservation, nutrient adequacy, and patient safety. You’ll hear Lara’s practical approach—starting with screening for eating disorders and nutrient status before prescribing—and learn how to design workflows that make guideline implementation realistic in busy clinical settings. Providers will leave with evidence-informed strategies to improve patient outcomes, minimize side effects, and support sustainable behavior change around GLP-1 therapy.

Transcript

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0:00.0

Today on the root cause medicine podcast, we're going to presume that there are going to be cases where the medication is useful, and there's going to be cases where it's probably best to avoid it.

0:11.7

Now, should we arrive at the decision tree where we are using the medication, what are some of the things that we have to consider?

0:18.4

There are three big things that come to mind when I'm making that decision.

0:22.6

Well, hello there and welcome to the Root Class Medicine podcast.

0:25.6

I'm your host for today, Dr. Kate Kresge, and we are covering something new in GLP1 prescribing.

0:31.6

In June of 2025, four major organizations collaborated on a joint release statement about GLP1's and best prescribing

0:38.9

practices.

0:39.9

It's called Nutritional Priorities to Support GLP1 Therapy for Obesity, a joint advisory

0:44.7

from the American College of Lifestyle Medicine, the American Society for Nutrition,

0:49.3

Obesity Medicine Association, and the Obesity Society.

0:52.7

Now, this is revolutionary because it describes a very

0:55.7

whole person approach to GLP1 prescriptions, including screenings we should be doing before prescribing,

1:01.2

muscle management, how to make sure that our clients are consuming a nutrient-rich diet

1:05.4

and the nutrient deficiencies and other medical conditions that we should absolutely be

1:10.3

screening them for before,

1:11.4

during, and after treatment.

1:13.2

Lara Zakaria is a phenomenal integrative pharmacist, IFM certified practitioner.

1:19.4

She's been teaching functional medicine for decades.

1:21.4

And when this report first dropped, she came out with a phenomenal LinkedIn post where she

1:26.5

broke down the science and the

1:28.3

recommendations and how clinicians could implement them in practice the next day.

1:32.8

I'm thrilled to have her on the show today to walk us through the science and what she

...

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