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Everyday Wellness with Cynthia Thurlow ™

BONUS: Women, Skin & Aging: A New Era of Skincare with Dr. Alessandra Zonari

Everyday Wellness with Cynthia Thurlow ™

Cynthia Thurlow

Alternative Health, Nutrition, Science, Life Sciences, Health & Fitness

4.81K Ratings

🗓️ 19 May 2025

⏱️ 63 minutes

🧾️ Download transcript

Summary

Today, we have another episode in our series of thoughtfully curated companies. This episode is sponsored by OneSkin, a company founded and led by an all-female team of PhD-level scientists. OneSkin is redefining how we think about aging, starting with the skin, our largest organ. I am delighted to introduce Dr. Alessandra Zonari as our guest today. Dr. Zonari is far from your typical scientist. She is a true visionary with a passion for longevity, skin regeneration, and an occasional karaoke jam. With degrees in biology and stem cell biology and a doctorate in skin regeneration and tissue engineering, Dr. Zonari brings a wealth of knowledge and a fresh perspective to our conversation today. Join us to learn more about OneSkin and how their products can reverse the effects of biological aging, helping your skin become stronger and more resilient as you age. IN THIS EPISODE YOU WILL LEARN: Dr. Zonari shares her mission to understand how skin can age healthier and stronger and reduce the risk of inflammation and diseases.  How the female-led research team at OneSkin brings a unique perspective to skincare How the OneSkin peptide can reverse 2.5 years of biological aging in just five days The unique way in which they test their products and measure biological aging at OneSkin  How estradiol loss during menopause exacerbates the accumulation of senescent cells and causes inflammation Some common misconceptions about skincare for women in perimenopause and menopause How lifestyle choices influence the aging process of the skin  Why we must protect the skin from environmental stressors to slow the aging process  How your skin cells can get reprogrammed to return to a youthful state How OneSkin developed a hair care line to address hair loss and thinning The importance of self-love and nourishing your body  ABOUT OneSkin:  Founded and led by an all-woman team of PhD-level scientists, OneSkin is transforming the way we think about aging, starting with the body’s largest organ, the skin. Our proprietary OS-01 (oh ess one) peptide is the first ingredient to reverse the biological age of skin by targeting cellular senescence, a key driver of aging. By targeting cellular senescence, the OS-01 peptide switches off the damaged cells that contribute to lines, wrinkles, and sagging skin. The result? Skin that looks and behaves younger. Our products are designed for young and mature skin, because it is never too early or too late to invest in your skin health! We create next-level skin care. BIO: Alessandra Zonari, PhD, OneSkin Co-Founder & CSO Alessandra is not your typical scientist. She is a visionary with a passion for longevity, skin regeneration, and the occasional karaoke jam. Growing up in a close-knit family in Brazil, Alessandra saw her grandparents struggle with age-related diseases, and she soon became fascinated by the possibility of using stem cells to redefine the aging process. After earning degrees in biology and stem cell biology and a doctorate in skin regeneration and tissue engineering, Alessandra joined OneSkin in 2017 as a founding member and Chief Scientific Officer. Her contributions include 20+ papers, three patents, and the development of their proprietary OS-01 peptide. Connect with Cynthia Thurlow   Follow on X Instagram & LinkedIn Check out Cynthia’s website Submit your questions to [email protected] Connect with Dr. Alessandra Zonari On the ONESKIN website ONESKIN on Instagram Interested in trying OneSkin for yourself? Visit oneskin.co/CYNTHIA and use code CYNTHIA for 15% off your first purchase!

Transcript

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0:00.0

Welcome to Everyday Wellness Podcast.

0:03.7

I'm your host, nurse practitioner Cynthia Thurlow.

0:07.5

This podcast is designed to educate, empower, and inspire you to achieve your health and wellness goals.

0:13.9

My goal and intent is to provide you with the best content and conversations from leaders in the health and wellness industry each week and

0:21.6

impact over a million lives.

0:29.5

Alessandra isn't your typical scientist.

0:31.8

She's a visionary with a passion for longevity, skin regeneration, and the occasional karaoke

0:36.8

jam.

0:46.3

She has a doctorate in skin regeneration and tissue engineering, and she joined one skin in 2017 as a founding member and chief scientific officer. Her contributions include 20 papers, three patents, and the development of their proprietary OS1 peptide.

0:59.4

Today we spoke about what inspired her to focus her research on cellular aging and skin health,

1:05.9

particularly peptides like OS01, how we can slow or reduce the biological aging of our skin, and how is this currently measured.

1:08.0

The impact of cellular senescence and why it becomes more important

1:12.4

during perimenopause and menopause. The impact of the key biological drivers of the aging

1:18.6

process in our skin and menopause. The impact of the loss of collagen and elastin with lower

1:24.0

levels of estrogen. Issues in the industry in terms of their approaches to skin care,

1:30.3

what makes skin aging different from aging and other organs, and the impact of lifestyle,

1:35.8

what is inflammation, how OS01 works at the cellular level to support aging skin,

1:43.5

including reducing inflammation and reducing

1:46.4

senescent cells, how it's different from other topical products like retinoids or

1:51.4

hyluronic acid, how we can navigate choosing skincare products aimed at longevity rather than

1:56.6

just symptom alleviation. What does the future skincare look like for middle age women?

2:01.5

And last but not least,

...

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