The Welcome, everybody to another episode of Dr. Matt and Dr. Mike's medical podcast.

I'm your host, Dr. Mark Todorovich.

And today I'm joined, as always, by my co-host.

Actually, no, I'm not.

I'm not.

For once, Matt isn't here. Now, this isn't because we've had a falling out

and I fired him and I told him it's over. After 10 years, this is done. No, that's not what happened. Matt's

sick. So the benefit of Matt being sick, that sounds horrible, but the benefit of Matt being sick is that

there's no interruption. I'm not going to get interrupted today. That might be a bad thing for you

because I do go off track sometimes. It also means you're probably going to get some better jokes

at the start of this podcast. So let me give you some. Here we go. What happens when your brain

sees a friend across the street?

It gives a brain wave. Okay, that's terrible. What continues to work even after it's fired?

A neuron. Yeah, that's just as bad. Why did the brain refuse to take a bath? It didn't want to be

brainwashed. All right, I'm sorry. This is a lot worse

than what Matt usually does. So I apologize. I won't do the jokes. What I will do, however,

is get started. Today we're talking about the blood brain barrier, the triple B, the big B.

So we're talking about this barrier that separates the brain proper. So the

parenkoma, right, so this is the main tissue of the brain, from the surrounding blood supply that

we know comes from the rest of the body, the systemic circulation. And it's really important that

there is a barrier

that separates out what is going from the bloodstream into the brain and what's going from

...