Big Idea: Struggling with High Blood Pressure and Inflammation? You Might Need to Improve Your Nitric Oxide—Here's How

Dhru Purohit Show

Dhru Purohit

Medicine, Health & Fitness, Alternative Health

4.7 • 3.4K Ratings

🗓️ 30 June 2025

⏱️ 46 minutes

🔗️ Recording | iTunes | RSS

🧾️ Download transcript

Summary

This episode is brought to you by Cozy Earth and Maui Nui. Each year, nearly 700,000 lives are lost to cardiovascular disease—and half of those individuals had no warning signs before their event. One major contributing factor? Low levels of nitric oxide, a vital molecule that supports healthy blood flow and keeps blood vessels flexible. The good news is that lifestyle changes—like diet, exercise, and proper supplementation—can naturally boost nitric oxide levels, helping to reduce your risk and support long-term heart health. Today on The Dhru Purohit Show, we’re revisiting one of our most talked-about moments with Dr. Nathan Bryan, all about why nitric oxide is the most underrated molecule for both short- and long-term health. Dhru and Dr. Bryan explore the connection between low nitric oxide levels and major conditions like heart disease, high blood pressure, Alzheimer’s, sexual dysfunction, and metabolic decline. They also dive into the biggest blockers of nitric oxide production, the top foods and lifestyle choices to naturally boost it, signs of deficiency, and so much more. Dr. Nathan Bryan is a leading expert in molecular medicine and nitric oxide research, with over 20 years of groundbreaking work and dozens of global patents. He’s the founder of Nitric Oxide Innovations, a company developing nitric oxide-based therapies to improve health worldwide. In this episode, Dhru and Dr. Bryan dive into: What happens in the body when we don’t produce enough nitric oxide (1:17) The link between nitric oxide and heart health (3:30) How nitric oxide is produced in the body (11:22) Habits that boost nitric oxide production (15:07) How mouthwash inhibits nitric oxide production (17:05) Nasal breathing and nitric oxide production (29:18) The impact of proton pump inhibitors on creating nitric oxide (32:23) Foods to avoid and transitioning to an anti-inflammatory diet (40:16) High blood pressure and its link to nitric oxide (42:17) Final thoughts (44:58) Also mentioned: Full episode with Dr. Nathan Bryan This episode is brought to you by Cozy Earth and Maui Nui. Right now, get 40% off your Cozy Earth sheets and sleepwear. Just head over to cozyearth.com/dhru and use code DHRUP. Right now, Maui Nui Venison is offering my listeners a limited collection of my favorite cuts and products. Just go to mauinuivenison.com/dhru to secure your access now —but hurry, supply is limited! Sign up for Dhru’s Try This Newsletter Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0	Hi everyone, Drew Prode here. We all know that maintaining a healthy blood pressure and
0:04.9	inflammation markers are two major keys to preventing chronic disease. And you may have heard
0:09.2	about nitric oxide in the context of heart health or maybe even related to athletic performance.
0:14.6	But what if I told you that nitric oxide might be the earliest marker, or at least one of
0:20.2	the earliest markers, in the development
0:22.3	of chronic disease, and that it has a far-reaching impact affecting everything from your
0:27.8	cardiovascular health, energy levels, and cognition. This is why nitric oxide is sometimes referred to
0:33.5	as the miracle molecule. And in today's episode, I'm sharing a portion of my conversation I had
0:38.8	with Dr. Nathan Bryan, all about how nitric oxide is produced in the body and how simple
0:44.8	lifestyle habits can dramatically improve your nitric oxide levels and your overall health.
0:50.9	Dr. Nathan Brian is, by the way, an international leader in molecular
0:54.6	medicine and nitric oxide biochemistry. He's been involved in nitric oxide research for the past
0:59.9	20 years, and his main seminal discoveries have resulted in dozens of U.S. and international patents.
1:07.1	So with all that being said, let's dive into my conversation with Dr. Nathan Bryan.
1:17.3	What happens in the body when we don't produce enough nitric oxide?
1:23.0	What's actually not taking place or what does take place that's actually not good for us.
1:29.3	Well, thanks, Drew. It's great to see you and thanks for the invitation to join you.
1:33.4	And you make a very important point. So to answer your question, we know that loss of nitric oxide
1:38.1	is the earliest event in the onset and progression of most, if not all chronic diseases.
1:42.5	So if you become deficient in nitric oxide, what happens?
1:45.6	Usually the first sign and symptom is an increase in your blood pressure or sexual dysfunctional,
1:51.8	what we call erectile dysfunction. That occurs in both men and women. You know, two out of three
	...

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