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What's a potential optimal dose of vitamin C?

Now this was a seminal paper published back in 1996 by Levine and colleagues and it was

really the first well-performed pharmacokinetic study.

Being at vitamin C dosing and how that related to blood vitamin C levels.

So that's what you're seeing here.

If you look here down below they gave anywhere from 500 mg all the way up to 2500 mg of

vitamin C per day and two divided doses so they gave it twice a day.

And what you can see here is the current RDA is producing very low blood vitamin C levels

of not even 30 micro molar but this was the current RDA at the time which was I think

around 60 mg and now the current RDA is 90 mg for men and 75 for women.

So these authors argue that 200 mg should be the new RDA based on blood level vitamin

C responses to an oral 200 mg dose.

And the reason why they chose 200 mg as they said well you don't want to be on this

very steep part of the sigmoidal curve for blood vitamin C levels because if you're

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