meta_pixel
Tapesearch Logo
Log in
Emergency Medicine Cases

Best Case Ever 29: Drug Induced Aseptic Meningitis

Emergency Medicine Cases

Dr. Anton Helman

Education, Health & Fitness, Courses, Medicine, Science

4.7602 Ratings

🗓️ 23 September 2014

⏱️ 10 minutes

🧾️ Download transcript

Summary

Dr. David Carr presents his third of EM Cases' Carr's Cases. This series features potentially debilitating diagnoses that may be thought of as 'zebras', but actually have a higher incidence then we might think - and if diagnosed early, can significantly effect patient outcomes. Dr. Carr tells the story of young woman with an MRSA supra pateller abscess who was put on trimethoprim sulfamethoxazole and presents looking very ill with a severe headache. Not only has trimethoprim sulfamethoxazole been implicated in aseptic meningitis, but NSAIDS, immunomodulators and antibiotics have also been implicated. The reason this is so important for ED practitioners to know, is that case reports of drug-induced aseptic meningitis have shown that symptoms will resolve completely within 24 hours, once the offending drug has been stopped. Not only that, but if the patient receives the drug again in the future, they are at risk for a more severe case of drug induced aseptic meningitis.

Transcript

Click on a timestamp to play from that location

0:00.0

Yes, this is E.MK's best case ever mini podcast series, and I'm your host, Dr. Anton Hellman.

0:29.4

This is the third of our series, Carr's cases, with the one and only Dr. David Carr.

0:35.4

This series, again, is about diagnoses that seem like they might be zebras,

0:39.4

but in fact, they're not so rare that you really need to know about. This particular one was

0:44.1

written up in the most recent C-GEM journal, along with one of our All-Star residents, Dr. Joel

0:49.0

Lockwood. So I'm working in a minor shift, and one of the jobs as being the minor doc is I get to review all the old lab work, all the abnormal cultures. That's a real fun part of our job, isn't it? So one of my charge nurses comes up to me and she says, Dave, you're going to kill me. I said, what are you talking about? So you remember that patient? You know, there was some patient who was here a few days ago. I showed you the cultural result. It was MRSA positive. You

1:11.3

weren't overly excited. It was an abscess. I said, yeah. He said, well, I called her to see how she was feeling like you asked. And she said, she feels horrible. So I'm bringing her in. And I said, oh, that's okay. I don't mind. If she feels horrible, we should see her. So, I don't know, two hours later on my shift, it's the

1:28.1

middle of July and I go see this 33-year-old young female. She's wearing a trench coat in a Montreal

1:33.7

Canadian's hat and she's head down, face down. Now, apart from she was wearing a Montreal

1:38.0

Canadian's hat, that wasn't the biggest problem here. The biggest problem here is it's July and

1:42.2

she's wearing a full trench coat and she's got rogers and she's lying face down in my minor area. I have no idea that this is the person

1:48.1

with the abnormal culture result, but then I realize this is her. It doesn't add up. So I said,

1:53.1

what's going on? She's a 33-year-old female who presented with a super pateller abscess around her left

1:59.5

knee. She was seen in our emerge about

2:01.5

three days prior, for which an incision and drainage was correctly done. Now, at that point,

2:07.1

the decision was made to give her some ANCEF, not a medication to cover MRSA or anything like that,

2:13.2

but she was given a dose of ANCEF and she was sent home. She came back to the emerge two days later and it was getting a little bit worse.

2:21.4

And the treating physician at that time did a really good job to improve the incision and

2:26.1

drainus.

2:26.5

And then he suggested placing her on SEPTRA for seven days, one tablet double strength.

2:32.5

And that seemed to be really doing the part. We got the

2:35.2

culture back two days later, so this is when I get involved, and it shows that she has MRSA. And

...

Please login to see the full transcript.

Disclaimer: The podcast and artwork embedded on this page are from Dr. Anton Helman, and are the property of its owner and not affiliated with or endorsed by Tapesearch.

Generated transcripts are the property of Dr. Anton Helman and are distributed freely under the Fair Use doctrine. Transcripts generated by Tapesearch are not guaranteed to be accurate.

Copyright © Tapesearch 2026.