5 • 716 Ratings
🗓️ 25 July 2019
⏱️ 12 minutes
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0:00.0 | Hey all, welcome back to the real-life pharmacology podcast. |
0:03.2 | I'm your host, pharmacist, Eric Christensen. |
0:06.8 | And today on the episode, I am going to cover Ben Stroping, |
0:12.5 | which the brand name for that medication is Cogentin. |
0:16.8 | Now, it's not a medication that's used incredibly often, |
0:20.1 | and at least in my practice, in my experience, |
0:25.2 | the most common situation I've seen it used for is drug-induced extraparaminal symptoms. |
0:34.8 | And the most common class of medications that cause these adverse effects are antipsychotics. |
0:41.9 | So these can be, you know, antipsychotics and obviously be super helpful in patients with |
0:47.2 | schizophrenia, for example, in reducing, you know, psychosis, hallucinations, delusions, things of that nature. However, they can |
0:57.2 | cause these movement adverse effects, which are called extra pyramidal symptoms. And so Benstropine |
1:05.9 | can be used to help manage this adverse effect. Now I do want to caution that the drug is not really |
1:16.1 | intended to be used for prophylaxis. So for instance, we don't give, you know, |
1:23.4 | risperidone and automatically give benzopine with it. We actually wait generally for these |
1:31.1 | patients to develop these adverse effects, and sometimes they don't have extra-paraminal symptoms, |
1:37.3 | but in the event that a patient is really, really responsive to the antipsychotic. |
1:48.9 | And we have maybe tried alternative agents, |
1:52.3 | and they're having these troublesome extraparaminal symptoms, |
1:55.3 | but we feel that the benefit of keeping it on board is actually worth it for the patient |
1:58.3 | in just managing those side effects. |
2:00.8 | So that's where |
2:01.5 | Benstropine I've seen it used most in that setting. Important differentiation, it is not recommended |
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