All-In Summit Highlights, Schools Could Block Social Media, FTC Chatbot Investigation, and Zoox hits Vegas | E2177
This Week in Startups
Jason Calacanis
4.4 • 1.3K Ratings
🗓️ 13 September 2025
⏱️ 89 minutes
🧾️ Download transcript
Summary
Today’s show:
On Friday’s TWiST, Jason, Alex, and Lon look back at some highlights from this week’s big All-In Summit in Los Angeles, including a fiery, no holds barred presentation from Palantir CEO Alex Karp, Elon Musk delving into the key challenges facing Optimus, and Tucker Carlson debating Mark Cuban on Ukraine. PLUS… why schools may start blocking social media apps, the FTC’s new investigation into social chatbots, AND omnidirectional Zoox robotaxis are headed to Las Vegas.
Timestamps:
- Welcome back to TWiST!
- (1:52) Jason’s thoughts on the killing of Charlie Kirk
- (10:34) Squarespace - Use offer code TWIST to save 10% off your first purchase of a website or domain at https://www.Squarespace.com/TWIST
- (10:52) Show Continues …
- (12:15) Reacting to All-In Summit highlights (Elon Musk, Alex Karp, Tucker Carlson, Mark Cuban)
- (21:23) AWS Activate - AWS Activate helps startups bring their ideas to life. Apply to AWS Activate today to learn more. Visit https://www.aws.amazon.com/startups/credits
- (22:18) Show Continues …
- (26:09) Palantir, Alex Karp, and debate dynamics
- (31:03) Public - Take your investing to the next level with Public. Build a multi-asset portfolio and earn 4.1% APY on your cash—with no fees or minimums. Start now at public.com/twist
- (32:13) Show Continues …
- (45:03) How the internet used AI tools to make sense of Charlie Kirk’s death
- (56:22) Why Jason thinks it’s smart to block social media during school hours
- (1:03:43) The FTC chatbot investigation leaves out Anthropic’s Claude… here’s why
- (1:13:27) Zoox robotaxis make their Vegas debut… Here’s how they’re different from Waymo
- (1:19:38) Are Tesla robotaxis headed for CA soon? Polymarket says… maybe
- (1:27:21) Closing remarks and banter
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Thank you to our partners:
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Transcript
Click on a timestamp to play from that location
| 0:00.0 | We could all disagree about so many things, but the senseless murder is just there's no place for this. |
| 0:05.3 | And it's a, it's in no way going to change what those kids are going to go through. |
| 0:14.3 | But we made a donation here on behalf of the This Week in Startups family to Charlie Kirk's kids' funds. |
| 0:25.3 | And encourage everybody to do the same. And gosh, |
| 0:29.9 | you know, there's nothing to say here other than I'm thinking about his family. And we're all thinking about that. And senseless murders for trying to model debate on college campuses is senseless, tragic, infuriating, and depressing. |
| 0:43.7 | And it's time for leadership from everybody who is part of these debates to step up and just say there's no room for this. |
| 0:53.6 | This week in startups is brought to you by Public. |
| 0:57.5 | You take investing seriously. |
| 0:59.6 | Public does too. |
| 1:01.4 | Build a multi-asset portfolio and earn an industry-leading 4.1% APY on your cash with no fees or minimums. |
| 1:10.1 | Learn more at public.com slash twist. AWS Activate. |
| 1:15.1 | AWS Activate helps startups bring their ideas to life. As you build and scale your business, |
| 1:20.9 | activate credits grow with you to support your changing needs. Apply to AWS Activate |
| 1:26.2 | today and receive up to $100,000 in credits. Visit |
| 1:30.5 | aWS.m. Amazon.com slash startups slash credits. And Squarespace. Turn your idea into a beautiful |
| 1:41.1 | website. Go to Squarespace.com slash twist for a free trial. When you're ready to |
| 1:46.1 | launch, use Offerco's Twist to save 10% off your first purchase of a website or domain. All right, |
| 1:51.6 | everybody, welcome back to this week in startups. I apologize for not shaving today and not |
| 1:57.1 | being suited up. Gentlemen, I am on the road. No rest for the weary had the amazing |
| 2:04.5 | All-in summit Monday, Tuesday, an incredible celebration of vibrant debate. And we'll get into that. |
| 2:11.3 | We'll have some videos of it. But I had to go Wednesday in order to book Vlad, my friend from Robin Hood, Alex. I said, hey, you got to come to the summit. Things are going great. Let's chop it up. He said, of course, but I'll come next year because I have the Robin Hood Summit in Vegas. And I said, well, what days is that? He said, Tuesday, Wednesday. I said, perfect. Come Monday. He's like, well, it's a bit much for me to come Monday and then go to Vegas. |
| 2:36.7 | I got this big thing. |
... |
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