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Science Magazine Podcast

A new generation of radiotherapies for cancer, and why we sigh

Science Magazine Podcast

Science Podcast

News Commentary, News, Science

4.2791 Ratings

🗓️ 2 October 2025

⏱️ 34 minutes

🧾️ Download transcript

Summary

First up on the podcast, Staff Writer Robert F. Service joins host Sarah Crespi to talk about a boom in nuclear medicine, from new and more powerful radioisotopes to improved precision in cancer cell targeting.   Next on the show, we talk about why we sigh. Maria Clara Novaes-Silva, a doctoral student at ETH Zürich, discusses how deep breaths cause minute rearrangements at the special interface where air meets lung. The lung flexibility granted by these deeper inhalations suggest people on ventilators might have better lung health if they were served a larger draught of air from time to time. This week’s episode was produced with help from Podigy. Authors: Sarah Crespi; Robert Service Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

This is a science podcast for October 2nd, 2025.

0:06.4

I'm Sarah Crespi.

0:07.7

First this week, staff writer Robert Service joins us to talk about a boom in nuclear

0:12.8

medicine for cancer, for more powerful radioisotopes to improved precision and cell targeting.

0:19.6

Next on the show, Why We Sigh,

0:22.3

researcher Maria Clara Nova Silva

0:24.2

discusses how deep breaths

0:26.5

cause tiny rearrangements

0:28.4

at the special interface where air needs lungs,

0:32.2

keeping them healthy and flexible.

0:46.8

Now we have Robert Service.

0:52.8

He wrote a story this week on a search in radio pharmaceuticals research or radioactive drugs for cancer.

0:55.8

Hi, Bob. Welcome back to the podcast.

1:01.4

Thank you so much. You know, I might have started this with why now, but that is like the whole story. There is so much going on right now with radio pharmaceuticals, whether it's sourcing where,

1:07.2

you know, the radioactive particles are coming from, the kinds of drugs they're making with it,

1:12.3

there's ongoing clinical trials, there's so much happening. We're going to get into all of that.

1:18.6

Let's start with how these drugs work and how the targeting works. I think this example that kind of

1:24.2

started things off with iodine is a really good place to kind of get people

1:28.7

oriented. Of course, yeah. Radiation in chemotherapy and cancer treatment has a very long history,

1:35.0

100 years. In most radiation treatment, still today is done by external beam radiation. That's where

1:43.0

they target a beam of radioactivity at a cancer or something

1:46.9

like that. But what we're talking about here are radiopharmaceuticals. So what they do is they link

...

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