#90 – Dmitry Korkin: Computational Biology of Coronavirus

Lex Fridman Podcast

Lex Fridman

Philosophy, Society & Culture, Science, Technology

4.7 • 13K Ratings

🗓️ 22 April 2020

⏱️ 130 minutes

🔗️ Recording | iTunes | RSS

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Summary

Dmitry Korkin is a professor of bioinformatics and computational biology at Worcester Polytechnic Institute, where he specializes in bioinformatics of complex disease, computational genomics, systems biology, and biomedical data analytics. I came across Dmitry’s work when in February his group used the viral genome of the COVID-19 to reconstruct the 3D structure of its major viral proteins and their interactions with human proteins, in effect creating a structural genomics map of the coronavirus and making this data open and available to researchers everywhere. We talked about the biology of COVID-19, SARS, and viruses in general, and how computational methods can

Transcript

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0:00.0	The following is a conversation with Dmitri Korkin.
0:02.6	He's a professor of bioinformatics and computational biology at WPI, Worcester Polytechnic Institute,
0:09.2	where he specializes in bioinformatics of complex diseases, computational genomics,
0:14.5	systems biology, and biomedical data analytics.
0:18.3	I came across Dmitri's work when in February, his group used the viral genome of the COVID-19
0:25.0	to reconstruct the 3D structure of its major viral proteins and their interaction with
0:30.6	the human proteins.
0:32.4	In effect, creating a structural genomics map of the coronavirus and making this data open
0:37.4	and available to researchers everywhere.
0:40.2	We talked about the biology of COVID-19, SARS, and viruses in general, and how computational
0:45.8	methods can help us understand their structure and function in order to develop antiviral
0:51.1	drugs and vaccines.
0:54.1	This conversation was recorded recently in the time of the coronavirus pandemic.
0:58.8	For everyone feeling the medical, psychological, and financial burden of the crisis, I'm sending
1:03.4	love to your way.
1:04.9	Stay strong, we're in this together.
1:07.0	We'll beat this thing.
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	...

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