693 - DoxyPEP: A "Morning-After Pill" for STIs
Public Health On Call
The Johns Hopkins Bloomberg School of Public Health
4.6 • 644 Ratings
🗓️ 29 November 2023
⏱️ 16 minutes
🧾️ Download transcript
Summary
An alarming rise in sexually transmitted infections like chlamydia, gonnorhea, and syphilis in the US calls for new prevention and treatment tactics. Dr. Matthew Hamill, a Johns Hopkins clinical researcher specializing in HIV and STIs, talks with Stephanie Desmon about DoxyPEP, or the use of antibiotic doxycycline after sexual contact. They discuss its effectiveness and availability, use in the context of antibiotic resistance, and why DoxyPEP isn't a silver bullet in the prevention of STIs.
Transcript
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| 0:00.0 | Welcome to Public Health On Call, a podcast from the Johns Hopkins Bloomberg School of Public Health, |
| 0:05.9 | where we bring evidence, experience, and perspective to make sense of today's leading health challenges. |
| 0:16.3 | If you have questions or ideas for us, please send an email to public health question at jh.h. |
| 0:22.6 | That's public health question at jh.h.u.org for future podcast episodes. |
| 0:29.6 | This is Lindsay Smith Rogers. |
| 0:32.6 | There has been a huge increase in sexually transmitted infections over the past decade. |
| 0:38.6 | There are no vaccines, and many of these infections can be hard to treat. |
| 0:43.5 | Today, Stephanie Desmond talks to Dr. Matthew Hamill, an expert on STIs at Johns Hopkins, |
| 0:49.5 | about a new tool in the works, having people take a dose of antibiotics after sex to prevent infections |
| 0:56.5 | from starting. And research suggests it works for some. Let's listen. Matthew Hamill, |
| 1:04.2 | thanks so much for joining me. Oh, it's my pleasure, definitely. Thank you for inviting me along. |
| 1:09.5 | So you're an expert in sexually transmitted infections, |
| 1:13.0 | and I've been reading about something called doxypep, and I'm wondering if you can please explain |
| 1:18.1 | what that is. Of course. Doxy stands for doxycycline, which is an antibiotic that we use |
| 1:23.9 | to typically to treat infections, but also to prevent infections. |
| 1:28.8 | And PEP stands for post-exposure prophylaxis, which is a long series of words, but really what |
| 1:35.3 | the idea is that an individual will take an antibiotic doxycycline after a sexual exposure to try and prevent them acquiring a sexually |
| 1:47.2 | transmitting infection. |
| 1:49.3 | And what kinds of infections are we talking about specifically? |
| 1:52.6 | Yeah, so we're talking about bacterial sexually transmitted infections. |
| 1:57.7 | So that is chlamydia, gonorrhea, and syphilis. |
| 2:01.4 | They're the three infections that have been studied in the context of doxycycline-Pet. |
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