69. What’s to blame for Insulin Resistance, Carbs or PUFAs? A very friendly debate with Ben Bikman, PhD

Paul Saladino MD podcast

Paul Saladino, MD

Medicine, Health & Fitness

4.8 • 2.7K Ratings

🗓️ 8 September 2020

⏱️ 135 minutes

🔗️ Recording | iTunes | RSS

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Summary

Benjamin Bikman earned his PhD in Bioenergetics and was a postdoctoral fellow with the Duke-National University of Singapore studying metabolic disorders. Currently, his professional focus as a scientist and professor (Brigham Young University) is to better understand the origins and consequences of metabolic disorders, including obesity and diabetes, with a particular emphasis on the role of insulin. He frequently publishes his research in peer-reviewed journals and presents at international science and public meetings.

Time Stamps

0:11:14 Podcast Begins

0:11:54 Ben's Background

0:17:53 The root of chronic disease

0:25:38 All about insulin

0:31:14 Regulation of free fatty acid metabolism by insulin in humans: role of lipolysis and reesterification https://www.semanticscholar.org/paper/Regulation-of-free-fatty-acid-metabolism-by-insulin-Campbell-Carlson/9be324b8af9ced5a8b7e1902257e3fb9308b4db1

0:31:51 Insulin stops lipolisis

0:34:35 Insulin's affect on the liver

0:40:10 Insulin and muscle cells

0:43:20 Why you want to increase protein as you age

0:48:47 Low Protein Intake is Associated with a Major Reduction in IGF-1, Cancer, and Overall Mortality in the 65 and Younger but Not Older Population https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988204/#:~:text=Low%20Protein%20Intake%20is%20Associated,Younger%20but%20Not%20Older%20Population&text=Cell%20Metab.,Author%20manuscript.

0:51:00 Animal-based diets optimize muscle protein sythesis

0:55:12 Industrial Seed oils have a fantastic publicist

0:58:05 Do carbs drive metabolic dysfunction?

1:07:07 Effect of sustained physiologic hyperinsulinaemia and hyperglycaemia on insulin secretion and insulin sensitivity in man https://link.springer.com/article/10.1007/BF00400466

1:07:42 How linoleic acid drives metabolic dysfunction

1:09:32 How linoleic acid drives metabolic dysfunction.

1:11:47 Low serum insulin in traditiona

Transcript

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0:00.0	Welcome to the Fundamental Health Podcast. I'm your host, Dr. Paul Saladino. This
0:10.6	podcast is the result of my relentless search to understand and correct the roots of chronic
0:15.1	disease and illness. In this podcast, I will share with you everything I have learned
0:18.9	about how to live the most healthy and radical life possible. Thanks for joining me on this
0:23.4	journey.
0:27.2	What is up you guys? I was recently on another podcast and the host asked me about my history
0:34.2	and where I've come from and I said, you know what? I think when I actually consider
0:39.9	that question, I am an explorer, a surfer who accidentally went to medical school twice.
0:47.8	I think that I've just been so fortunate to do a lot of amazing things in my life to spend
0:52.6	time in beautiful places, in the wilderness, in the mountains, skiing powder, climbing
0:58.5	mountains, surfing waves. And I think that even when I was in Jackson Hole, when I was
1:05.0	riding up the ski lift and it was a powder day, I just wanted to share the joy of skiing
1:12.0	down through powder with people who are visiting. One of the greatest parts of my life, one
1:17.5	of the greatest joys I've had in my life is sharing things that bring my life meaning
1:21.1	and purpose and things that I find beautiful with other people. And I realized as I answered
1:26.7	that question on the podcast, that is a reason that I do what I do. That is the reason that
1:31.8	I think about how human health, because what more interesting puzzle is there than how
1:39.0	to help all of us be as optimally healthy as possible. That is the lens through which
1:44.3	we experience the world. That is the lens through which we experience life. And I have been
1:49.2	so fortunate to have so many beautiful, memorable, incredible experiences with friends and family,
1:56.3	in my own good health and in the wilderness that I just want to share all of that with you.
2:01.9	And so I hope this podcast brings you value. And I hope that what we're doing at Harden
	...

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