Coming up on today's show.

I don't think that many doctors get this, is that energy delivery mechanisms are at the root of all pathological conditions, almost without exception.

They are vital in preventing and reversing dementia, preventing and treating cancer, preventing and treating heart disease as well.

If you produce energy anaerobically to generate lactic acid, you get two molecules of ATP.

If you do it aerobically via mitochondria from one molecule of acet, you get 36 molecules of ATP.

So it's much more efficiently burning stuff aerobically.

Lactic acid inhibits mitochondria and eventually you crash down, you kill over.

Those are the five supplements that I routinely recommend for anybody with a pathological fatigue.

Take the mitochondrial package. I'd probably add in creatine as well because that is a proven

benefit for improving mitochondrial function and therefore bigger muscles. So energy is everything.

Energy is the difference between life and death.

It is vital.

Sarah, one of your favorite areas to talk about is fatigue.

And right off the bat, let's jump in that subject.

Go deep.

But what I'm curious, how does that clinical picture differ from somebody

just burning the candle at both ends and being tired? It doesn't. It's exactly the same.

And the point here is the principles that apply to the treatment of fatigue apply to those who

are pathologically fatigued, those who have

normal levels of energy who would like maybe more energy, and improve the performance of top

athletes. So it applies across the board. Now, what I call pathological fatigue is when you pay for it

the next day. And guess what? If athletes push themselves to their limit,

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