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Energized with Dr. Mariza

663: From Wired and Tired to Calm and Energized: The GABA-Mitochondria Connection + How to Fix It at the Cellular Level with Dr. Scott Sherr

Energized with Dr. Mariza

Dr. Mariza Snyder

Medicine, Health & Fitness, Alternative Health

4.8 • 974 Ratings

🗓️ 18 July 2025

⏱️ 60 minutes

🧾️ Download transcript

Summary

Ever feel wired… yet exhausted? Or anxious… yet depleted? In this episode, I’m sitting down with Dr. Scott Sherr, a visionary physician and expert in cutting-edge mitochondrial and nervous system healing, and he unpacks why so many women in midlife feel overstimulated and underpowered at the same time.  We dive into the role of GABA, the calming neurotransmitter your body craves, and why it’s often depleted during midlife, contributing to the anxiety, insomnia, and mood dips that leave you feeling unlike yourself.  Dr. Sherr also explains how mitochondrial dysfunction silently sabotages your energy, sleep, and even your joy—and what you can do to restore it naturally and effectively.  This conversation is packed with practical, science-backed strategies to help you step out of the cycle of stress and burnout and into a state of calm, clear, vibrant energy.  Ready to reclaim your vitality at every age? This podcast is for you!  Dr. Schott Sherr  Dr. Scott Sherr is a Board Certified Internal Medicine Physician Certified to Practice Health Optimization Medicine (HOMe) and a Hyperbaric Oxygen Therapy (HBOT) specialist. He’s the COO of Troscriptions, which offers formulations for optimal energy, focus, sleep, and stress support. He’s also the VP of Health Optimization Medicine and Practice (HOMe/HOPe), the nonprofit arm of Troscriptions, which trains practitioners on optimizing health rather than treating disease. IN THIS EPISODE The biggest factors that shift our metabolic energy  What is GABA, and why does it help balance our nervous system?  Natural ways to support the GABA system  Supplementation to support the GABA system  How to support healing and enhance mitochondrial function  How methylene blue helps support mitochondrial function About Dr. Scott’s nonprofit: Health Optimization Medicine (HOMe) QUOTES “A big thing I've seen recently is tons of anxiety, tons of insomnia, tons of depression related to this inability to calm down, to turn our brains off. And some of those hormones that are transitioning as you go through the perimenopausal state are a big part of this.” If we really want to focus on holistically improving your sleep, relationships, and energy,  the primary focus needs to be downregulating your sympathetic nervous system and increasing your parasympathetic with the GABA enhancement aspect.” “That's a really cool way of holistically enhancing the GABA system without causing GABA depletion or GABA deficiency on its own.” RESOURCES MENTIONED Troscriptions: use code ENERGIZED for 10% off all things in the store!  Home Hope Org Dr. Scott Sherr’s Website  Dr. Scott’s Instagram  Preorder The Perimenopause Revolution HERE RELATED EPISODES  #635: The Connection Between Your Gut, Inflammation, Mood, and How to Start Healing Your Microbiome with Tina Anderson#648: This Changes Everything: The Perimenopause Revolution Every Woman Needs Now#609: Non-Negotiable Advice I Would Give My Early Perimenopausal Self#572: How to Know You are in Perimenopause Including the 40+ Symptoms Associated with Declining Hormones

Transcript

Click on a timestamp to play from that location

0:00.0

We have about 70,000 thoughts per day. That's on average. And when we're stressed,

0:07.4

when we have a lot of anxiety, when we're depressed, that thought generator, our brain, goes up to 120,000

0:13.4

thoughts per day. And so what I tell my patients all the time is that please don't believe everything

0:18.2

you think. 70,000 thoughts a day.

0:23.0

That's a lot of thoughts, even 120,000.

0:27.1

Welcome back to the energized with Dr. Marisa podcast.

0:31.8

I'm your host, Dr. Marisa, and I'm here to help you rock your hormones,

0:36.9

optimize your metabolic health, and feel energized in your body so that you can age powerfully and wake up feeling amazing

0:39.7

in for many years to come. Let's jump on in. Let me ask you something. Are you forgetting words

0:46.7

mid-sentence or waking up at 3 a.m. wired and anxious or gaining weight even though nothing has

0:54.1

changed or maybe your brain and body

0:56.6

are short-circuiting, yet no one warned you. If this sounds familiar, you are not alone,

1:03.4

and you are definitely not broken. You're likely in perimenopause. And this is the revolution

1:09.8

you've been waiting for. I wrote the perimenopause

1:13.0

revolution because I was right where you are, confused, exhausted, and desperate for answers that didn't

1:19.5

sound like, let's just wait it out. This book is for every woman who's been dismissed, gaslit,

1:25.5

or baffled by what's happening to her body.

1:28.1

It's a science-backed, no-fluff guide to balancing hormones, reviving your metabolism, clearing

1:33.9

your brain fog, and actually feeling like yourself again. Inside, you'll learn why your

1:38.9

metabolism shifts, why brain fog and muscle loss aren't just aging and how to turn this transition into your

1:45.3

power move for the next 40 years. And when you pre-order now, you'll get my exclusive $500

1:52.1

value perimenopause power toolkit instantly packed with everything you need to step fully

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