66 – PMDD and mental health: what’s really going on?
The Dr Louise Newson Podcast
Dr Louise Newson
4.7 • 933 Ratings
🗓️ 14 May 2026
⏱️ 31 minutes
🧾️ Download transcript
Summary
What if severe changes in your mental health were being driven by your hormones?
In this episode, Dr Louise Newson is joined by Dr Isabella Sillar, an Australian doctor, who shares her powerful and deeply personal experience of living with premenstrual dysphoric disorder (PMDD). Despite being in medical training, Isabella struggled for years with severe symptoms including suicidal thoughts, repeated misdiagnoses and treatments that failed to address the underlying cause.
They explore how hormonal fluctuations can influence mental health, why PMDD is so often misunderstood and the consequences of treating symptoms without considering hormones. Isabella also shares how finding the right treatment transformed her life, and how her experience has shaped the way she now supports her own patients.
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Transcript
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| 0:00.0 | So Izzy, it's great to have you on my podcast. You're a doctor over in Australia. I'm a doctor over in the UK. And guess what? We see similar patients with similar problems. But also, we've learned a lot on the way. Like our own personal journey, professional journey. Every day we're learning new things. And medicine is an art and a science. You know, |
| 0:22.7 | you have to know the science and physiology when we're talking about hormones, but actually |
| 0:27.6 | putting it into clinical practice, listening to our patients, understanding the nuances of |
| 0:32.7 | prescribing. You know, we learn so much. And it's great talking to you because, you know, we have the similar |
| 0:39.1 | challenges, similar problems and similar patients. So thank you for coming today. My pleasure. I'm so |
| 0:44.5 | excited to be here and just talking a little bit more about, you know, my own personal journey and |
| 0:49.0 | where I think medicine is going to go for women's health over the coming years. It's a really |
| 0:53.2 | exciting time. We're absolutely in the trenches of turning things around and I think it's going to go for women's health over the coming years. It's a really exciting time. We're absolutely in the trenches of turning things around. |
| 0:56.7 | And I think it's one of those ones where, you know, I've had the privilege of looking behind the curtain being a medical practitioner. |
| 1:03.5 | But for a number of years, I was really quite unwell during my early uni years and, you know, nearly was successfully taking my life like it was an awful time. |
| 1:13.1 | And now that I'm stable on treatment, I've come such a long way. |
| 1:16.5 | And so, yeah, the whole concept around premenstrual dysphoria disorder, I'm excited to talk about my journey. |
| 1:22.6 | I really wouldn't be surprised if there's probably going to be some tears with us chatting today. |
| 1:27.0 | Because it's a hard story, but I think it's one that I really do need to share, |
| 1:31.8 | that it's, you know, it's hard for clinicians as well to be heard in this space. |
| 1:36.7 | And I was gaslit awfully during my time. |
| 1:40.2 | And it really took me having to take control. |
| 1:43.3 | And I was just really fortunate that I had incredibly supportive parents. |
| 1:46.5 | I wouldn't be here with them having helped get me through this journey. |
| 1:50.7 | And I just think of all the women out there who may not have that support or, you know, |
| 1:54.5 | they're juggling busy families and it breaks my heart. |
| 1:57.7 | So whatever I can do to help now is a, as a health practitioner who sees a lot of |
... |
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