Welcome to the Mind Buddy Green podcast. I'm Jason Wachib, founder and co-CEO of My Buddy Green and your host.

Your skin is one of the most powerful windows into how well you're aging. Those freckles, fine lines,

and sudden overnight changes we all notice were actually reflecting deep cellular shifts happening

throughout the body. And today's guest is here to change the way you think about skin altogether.

Dr. Saranya Wiles is a dermatologist, regenerative medicine scientist, and the director of

regenerative dermatology and skin longevity lab at the Mayo Clinic. Her research sits at the

cutting edge of aging biology,

looking at how cellular senescence, wound healing, inflammation, and regenerative therapy

shaped not only how our skin looks, but how it functions as a true longevity organ. In today's show,

we'll dive into some fascinating topics, including how your skin reflects systemic aging and why it may be your most visible biomarker of long-term health.

We also cover what zombie cells actually are and how they accelerate both skin aging and whole body aging as well.

Plus, you learn about the five pillars of skin longevity and the future of regenerative dermatology.

This episode is packed with actionable insights.

Let's dive in.

So you started in dermatology and regenerative medicine.

What shifted your focus from aesthetics toward the deeper biology of aging skin.

Skin health is an incredible part of how we age systemically.

Skin is our largest organ.

Think about it as our longest relationship.

And it's our most visible biomarker of how we're aging on the inside.

So looking at skin was a natural way to see how

cues of systemic aging and systemic health could just present on your skin. So at Mayo Clinic,

...