Is it better to have say like a bolus of nitrates at three times you know during the day at three different meals or is it better to have them spread out more through the day?

Basically how often is the ideal of taking in nitrates to have the best

effect? Well the data, the clinical data, if we look at regulation of blood pressure and the impact on exercise performance or athletic performance.

We know that we need at least 300 to 500 milligrams as a bolus as a single serving right so taking in at once

You're not going to get the effect if you're taking 100 milligrams in a meal for breakfast 100 milligrams for lunch you need it as a bolus all at once

But the beauty of this pathway is once you consume that it takes 90 minutes for this to become activated

Now for the next 6-8, ten hours, we're slowly

titrating that system and slowly generating nitricoxet over time. So the best bang for your buck is going to be

all you need is just one kind of bolus, whether it's ideally at lunch or dinner or whenever throughout the day, you know, depending upon what you're going to be doing if you're about to run a race or do a you know a marathon or triathlete then you probably want to do that before at least 90 minutes before.

So yeah I think and what we're finding is there's really no added benefit to doing more, right? The body kind of self-regulates.

You give it what it needs, it's going to take the nitric oxide, generate it upon demand, but

giving more nitrate is not going to always generate more nitricoxide to see better performance better regulation of blood flow or blood pressure

Important we got into that because you took it the other way. I was talking more about like having little

doses throughout the day to keep topped up. But you're saying you've got to make sure you're hitting that

bullus with enough in one serving to actually have the impact.

So if you were to do what I was talking about,

you wouldn't have the same impact on the body.

You got to have enough in one serving

to have the impact.

Because it goes back to this 5% reduction efficacy, right?

25% uptake in the gut, 20% reduction by the oral bacteria.

So let's just say if you, if you're taking in 100 milligrams of nitrate you're going to generate 5 milligrams of nitride and that's not going to be enough to really see any vasoactive activity dilate blood vessels normal normalize blood pressure, induced mitochondrial biogenesis, improved

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