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Bourbon Pursuit

543 - The Dangers of Binge Drinking to our Health with Dr. Ulysses Wu

Bourbon Pursuit

Bourbon Pursuit

Food, Leisure, Arts, Hobbies

4.9866 Ratings

🗓️ 4 December 2025

⏱️ 82 minutes

🧾️ Download transcript

Summary

Is your love of high-proof, perfectly aged bourbon actually good for you? Or are we all just telling ourselves that? Today, we're tackling the elephant in the whiskey room with the science: Dr. Ulysses Wu (Yuli), the Chief Epidemiologist at Hartford HealthCare. Uly's personal journey is wild—from corporate finance to infectious diseases—and now he focuses on the intersection of alcohol, health, and longevity. He joins us to share his personal bourbon journey and how he accidentally procured some seriously rare Stitzel-Weller when nobody was looking. In this eye-opening episode, we dive into: The Calorie Problem for barrel-proof bourbon, Uly's concept of "firewalls" (the human ability to curb excess), why robust long-term health studies on alcohol are so difficult to conduct, and the profound psychological impact of bourbon, which Uly calls a "time machine" for positive memories. This is a mandatory listen for anyone who loves brown water and wants to understand the science behind drinking healthily and responsibly. Show Notes: Introduction to Dr. Ulysses Wu (Uly), Chief Epidemiologist at Hartford HealthCare Uly’s surprising career shift from corporate finance to infectious diseases The connection between alcohol, health, and longevity Uly's personal bourbon journey, including the accidental procurement of rare Stitzel-Weller Scientific discussion on the true caloric content of barrel-proof bourbon Analysis of "firewalls"—the psychological ability to prevent excess in consumption Challenges of conducting robust, long-term health studies on alcohol consumption The psychological power of bourbon as a "time machine" for positive memory creation Advice for drinking bourbon responsibly and healthily Alcohol and Health Research and Data from Dr. Wu Support this podcast on Patreon Learn more about your ad choices. Visit megaphone.fm/adchoices

Transcript

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0:00.0

Bourbon is another one of those things. I cannot think of a certain time where I've had bourbon at any given moment and my mind hasn't been transformed to another point in time as a point of reference. I don't do that with vodka. I don't do that with, you know, seltzers, but I don't even remember my first seltzer. But bourbon, there is always a significance, whether it is a location

0:22.3

or time in memory. And that is one of the most powerful psychological, addicting things that I think

0:29.9

keeps us going back to that well to a certain extent. This is Bourbon Pursuit, the official podcast of Bourbon, bringing to you the best in news, reviews, and interviews, with people making the bourbon whiskey industry happen,

0:54.7

and I'm one of your hosts, Kenny Coleman.

0:56.7

Is your love for high-proof, perfectly aged bourbon actually good for you?

1:01.8

Or are we just telling ourselves that as we reach for the second pour?

1:05.6

Today, we're finally tackling the elephant in the whiskey room,

1:09.8

and we brought the science to back it up.

1:12.3

We're joined by Dr. Ulysses Wu, or he goes by Uly.

1:15.5

He's the chief epidemiologist at Hartford Health Care.

1:19.1

Uly's personal journey, it's kind of wild.

1:21.4

He went from corporate finance to then to the front lines of infectious diseases, and now

1:25.7

focuses on the intersection of alcohol, health,

1:28.4

and longevity. He shares his own bourbon journey with us, including the incredible story

1:33.2

of how he procured probably some of the most rare stitzelweller bottles on the planet,

1:37.8

but it was a time when nobody was really looking for them. However, in this eye-opening episode,

1:42.4

we dive not only into the calorie problem for barrel-proof bourbon,

1:45.9

but even the studies that show alcohol and cancer research, there could be a correlation.

1:51.0

And we also get into Yuli's concept of firewalls, the human ability to curb excess.

1:56.0

We explore why robust long-term health studies on alcohol are so difficult and how they're really impossible

2:01.5

to conduct and perhaps most profoundly the powerful psychological impacts of bourbon, which

2:06.8

usually calls a time machine for positive memories. This is one of those episodes that I encourage

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