#511 Alzheimer's Disease: Updates in Diagnosis and Treatment

The Curbsiders Internal Medicine Podcast

Health & Fitness, Medicine, Science, Higher Education, Education

4.8 • 3.1K Ratings

🗓️ 12 January 2026

⏱️ 77 minutes

🔗️ Recording | iTunes | RSS

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Summary

Blood-based Biomarkers, Anti-Amyloid Therapies and Beyond

From blood-based biomarkers to anti-amyloid treatments, join us as we explore the latest in Alzheimer’s disease diagnosis and treatment with Dr. Halima Amjad. This episode will equip you to guide your patients about the latest Alzheimer’s diagnostics as well as eligibility, risks and monitoring for anti-amyloid therapies.

Intro
Case
Cognitive and functional history reminders
Diagnosing Alzheimer’s Disease
Blood-based biomarkers
Anti-amyloid therapy indications, eligibility and contraindications
Patient counseling and treatment decisions
ARIA
Key takeaways
Outro

Credits

Written and Produced by: Natalie Barrett DO, Rachel K Miller MD
Show notes, cover art and infographic: Natalie Barrett DO, Rachel K Miller MD, Leah Witt MD
Hosts: Matthew Watto MD, FACP; Paul Williams MD, FACP
Reviewer: Sai S Achi MD, MBA,FACP
Showrunners: Matthew Watto MD, FACP; Paul Williams MD, FACP
Technical Production: PodPaste
Guest: Halima Amjad, MD

Disclosures

Dr. Amjad reports financial relationships with Centene (Advisor) and Craniometrix (Advisor). Relationships have not ended. The Curbsiders report no relevant financial disclosures.

The production of this episode was supported by the Penn Geriatrics AGE-SMART Geriatric Workforce Enhancement Grant. This podcast content is solely the responsibility of the authors and does not necessarily represent the official views of the Health Resources and Services Administration or the U.S. Department of Health and Human Services.

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Transcript

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0:00.0	Hey, before we get to the show, I wanted to remind you to check out our Patreon at patreon.com
0:05.5	slash curbsiders.
0:06.7	If you haven't signed up yet, sign up now to get ad-free episodes, twice-monthly bonus episodes,
0:11.9	and a whole bunch of other cool stuff at patreon.com slash curbsiders.
0:19.4	Paul, three conspiracy theorists walk into a bar.
0:27.0	I feel like I could puzzle this one out.
0:29.1	You probably could.
0:30.5	But not in a way that won't bore our listeners.
0:32.7	All right, go on.
0:33.9	You can't tell me that's not a coincidence.
0:55.2	That's a good one. Yeah coincidence that's a good one yeah that's pretty good the okay the curbsiders podcast is for entertainment education and information purposes only and the topics discussed should not be used solely to diagnose treat cure or prevent any diseases or conditions for the more of the views and statements expressed on this podcast are solely those of the host and should not be interpreted to reflect official policy or position of any entity aside from possibly cash like more honestable and affiliate outreach programs if indeed there are any in fact there are none pretty much we aren't responsible if you
0:58.4	screw up you should always do your own homework and let us know when we're wrong.
1:05.3	Welcome back to the curbsiders. I'm Dr. Matthew Frank Guado, here with my great friend in America's primary care physician,
1:14.5	probably the primary care physician, Dr. Paul Nelson Williams.
1:19.1	Hey, Paul.
1:20.0	Yeah, probably.
1:20.8	Hey, Matt.
1:21.2	How are you?
1:22.2	I'm doing well.
1:22.9	Paul, this is an episode.
1:25.0	We talked about dementia.
1:26.4	We talked about plasma biomarkers we talked about
	...

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